Caspase Family Fluorometric Substrate Kit II Plus (ab102487)

Overview

  • Product nameCaspase Family Fluorometric Substrate Kit II Plus
    See all Caspase Family kits
  • Tests
    9 x 25 assay
  • Sample type
    Adherent cells, Suspension cells
  • Assay typeEnzyme activity
  • Product overview

    Abcam's Caspase Family Fluorometric Substrate Kit II Plus provides ready-to-use fluorometric substrates for assaying activities of members of caspase family proteases. All substrates are provided in liquid ready-to-use form.
    Visit our FAQs page for tips and troubleshooting.

  • Tested applicationsSuitable for: Functional Studiesmore details

Properties

  • RelevanceCaspases are members of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.
  • Cellular localizationCytoplasmic
  • Alternative names
    • CASP
    • CASP 2
    • CASP1
    • CASP2
    • Caspase
    • Caspase 1
    • Caspase 1 apoptosis related cysteine peptidase
    • Caspase 2
    • Caspase 2 apoptosis related cysteine peptidase
    • ICE
    • ICH 1 protease
    • ICH 1L
    • ICH 1L/1S
    • ICH1
    • IL 1 beta converting enzyme
    • IL1BC
    • Interleukin 1 B converting enzyme
    • Interleukin 1 beta convertase
    • Interleukin 1 beta converting enzyme
    • NEDD 2
    • NEDD2
    • NEDD2 apoptosis regulatory
    • Neural precursor cell expressed developmentally down regulated 2
    • Neural precursor cell expressed developmentally down regulated protein 2
    • P45
    • Protease ICH 1
    see all

Applications

Our Abpromise guarantee covers the use of ab102487 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Functional Studies Use at an assay dependent dilution.

Protocols

References for Caspase Family Fluorometric Substrate Kit II Plus (ab102487)

ab102487 has not yet been referenced specifically in any publications.

Product Wall

Thank you very much for contacting us with your questions.

We do have some panels for caspase activity measurement:

1) Ab102486: Includes substrates for caspases 1,2,3,5,6,8, and 9. It does not include substrates for caspases 4 and ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"