Overview

  • Product name
  • Description
    Rabbit polyclonal to CASS4
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 609-639 of Human CASS4 isoform 1 (NP_065089.2, NP_001157588.1) and isoform 2 (NP_001157586.1).

  • Positive control
    • MDA-MB435 cell line lysatesm

Properties

Applications

Our Abpromise guarantee covers the use of ab116022 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 87 kDa.

Target

  • Function
    Possible docking protein which may play a role for tyrosine-kinase-based signaling related to cell adhesion. Regulates FAK activity, focal adhesion integrity, and cell spreading.
  • Tissue specificity
    Expressed abundantly in lung and spleen. Also highly expressed in ovarian and leukemia cell lines.
  • Sequence similarities
    Belongs to the CAS family.
    Contains 1 SH3 domain.
  • Post-translational
    modifications
    Phosphorylated on tyrosines by SRC.
  • Cellular localization
    Cytoplasm > cytoskeleton. Cell junction > focal adhesion.
  • Information by UniProt
  • Database links
  • Alternative names
    • C20orf32 antibody
    • Cas scaffolding protein family member 4 antibody
    • CAS4 antibody
    • CASS4 antibody
    • CASS4_HUMAN antibody
    • HEF-like protein antibody
    • HEF1-EFS-p130Cas-like protein antibody
    • HEFL antibody
    • HEPL antibody
    • OTTHUMP00000031328 antibody
    • OTTHUMP00000031329 antibody
    see all

Images

  • Anti-CASS4 antibody (ab116022) at 1/100 dilution + MDA-MB435 cell line lysates at 35 µg

    Predicted band size : 87 kDa

References

ab116022 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab116022.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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