Anti-Catalase (phospho Y385) antibody (ab59429)

Overview

  • Product nameAnti-Catalase (phospho Y385) antibody
    See all Catalase primary antibodies
  • Description
    Rabbit polyclonal to Catalase (phospho Y385)
  • Specificityab59429 detects endogenous levels of Catalase only when phosphorylated at tyrosine 385.
  • Tested applicationsSuitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic phosphopeptide derived from human Catalase around the phosphorylation site of tyrosine 385 (A-N-YP-Q-R).

  • Positive control
    • Human brain tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab59429 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/20000.
IHC-P Use at an assay dependent concentration.

Target

  • FunctionOccurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
  • Involvement in diseaseDefects in CAT are the cause of acatalasia (ACATLAS) [MIM:115500]; also known as acatalasemia. This disease is characterized by absence of catalase activity in red cells and is often associated with ulcerating oral lesions.
  • Sequence similaritiesBelongs to the catalase family.
  • Post-translational
    modifications
    The N-terminus is blocked.
  • Cellular localizationPeroxisome.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cas1 antibody
    • CAT antibody
    • CATA_HUMAN antibody
    • Catalase antibody
    • Cs1 antibody
    • MGC138422 antibody
    • MGC138424 antibody
    see all

Anti-Catalase (phospho Y385) antibody images

  • ab59429, at a 1/50 dilution, staining Catalase in paraffin embedded human brain tissue by Immunohistochemistry in the absence (left image) or presence (right image) of the phosphopeptide.

References for Anti-Catalase (phospho Y385) antibody (ab59429)

ab59429 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"