Anti-Cathelicidin antibody [mAbcam 58387] (ab58387)

Overview

  • Product name
    Anti-Cathelicidin antibody [mAbcam 58387]
    See all Cathelicidin primary antibodies
  • Description
    Mouse monoclonal [mAbcam 58387] to Cathelicidin
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 150 to the C-terminus of Human Cathelicidin.

  • Positive control
    • This antibody gave a positive signal in human spleen tissue lysate.
  • General notes

    This antibody clone is manufactured by Abcam.


    CAP18 is the only human cathelicidin found so far and closely resembles CRAMP, the sole member of this gene family in mice. LL-37 is the 37 amino acid C-terminal antibacterial protein.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • Purity
    IgG fraction
  • Primary antibody notes
    CAP18 is the only human cathelicidin found so far and closely resembles CRAMP, the sole member of this gene family in mice. LL-37 is the 37 amino acid C-terminal antibacterial protein.
  • Clonality
    Monoclonal
  • Clone number
    mAbcam 58387
  • Myeloma
    Sp2/0-Ag14
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab58387 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 10 µg/ml. Detects a band of approximately 19 kDa (predicted molecular weight: 19 kDa).

Target

  • Function
    Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.
  • Tissue specificity
    Expressed in bone marrow and testis and neutrophils.
  • Sequence similarities
    Belongs to the cathelicidin family.
  • Post-translational
    modifications
    The N-terminus is blocked.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • 18 kDa cationic antimicrobial protein antibody
    • Antibacterial peptide LL-37 antibody
    • Antibacterial protein FALL-39 antibody
    • CAMP antibody
    • CAMP_HUMAN antibody
    • CAP 18 antibody
    • CAP-18 antibody
    • CAP18 antibody
    • Cathelicidin antimicrobial peptide antibody
    • Cathelin-like protein antibody
    • Cathelin-related antimicrobial peptide antibody
    • CATHL3 antibody
    • Cationic antimicrobial protein, 18-KD antibody
    • CLP antibody
    • Cnlp antibody
    • Cramp antibody
    • CRAMP, mouse, homolog of antibody
    • FALL 39 antibody
    • FALL-39 peptide antibiotic antibody
    • FALL39 antibody
    • hCAP 18 antibody
    • hCAP-18 antibody
    • hCAP18 antibody
    • HSD26 antibody
    • LL37 antibody
    • MCLP antibody
    • Peptide antibiotic, PR-39, porcine, homolog of antibody
    see all

Images

  • Anti-Cathelicidin antibody [mAbcam 58387] (ab58387) at 10 µg/ml + Human spleen tissue lysate - total protein (ab29699) at 20 µg

    Secondary
    Mouse IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 19 kDa
    Observed band size : 19 kDa
    Additional bands at : 60 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 30 seconds

References

ab58387 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab58387.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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