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Rabbit polyclonal to Cathepsin B
ab30443 recognises liver Cathepsin B. Does not crossreact with Cathepsin L or Cathepsin H.
Full length native protein (purified): Cathepsin B from Human liver.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4
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Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/250 - 1/500.
1/1000 - 1/5000. Predicted molecular weight: 38 kDa.
Use at an assay dependent concentration. See Abreview.
Use at an assay dependent concentration. PubMed: 24833013
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
Belongs to the peptidase C1 family.
Lysosome. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Information by UniProt
Amyloid precursor protein secretase antibody
APP secretase antibody
This product has been referenced in:
et al. AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation. Aging Cell 15:416-27 (2016).
Read more (PubMed: 26890602) »
et al. Quantitative expression and localization of cysteine and aspartic proteases in human abdominal aortic aneurysms. Exp Mol Med 46:e95 (2014).
Read more (PubMed: 24833013) »
See all 4 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"