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Storage instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4
Concentration information loading...
Purity IgG fraction
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/250 - 1/500.
1/1000 - 1/5000. Predicted molecular weight: 38 kDa.
Use at an assay dependent concentration. See Abreview.
Use at an assay dependent concentration. PubMed: 24833013
Function Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
Sequence similarities Belongs to the peptidase C1 family.
Cellular localization Lysosome. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Information by UniProt
Amyloid precursor protein secretase antibody
APP secretase antibody
References for Anti-Cathepsin B antibody (ab30443)
This product has been referenced in:
et al. Quantitative expression and localization of cysteine and aspartic proteases in human abdominal aortic aneurysms. Exp Mol Med 46:e95 (2014).
Read more (PubMed: 24833013) »
et al. Lipid peroxidation products reduce lysosomal protease activities in human retinal pigment epithelial cells via two different mechanisms of action. Exp Eye Res 90:261-6 (2010).
Read more (PubMed: 19895809) »
See all 2 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"