Overview

  • Product nameAnti-Cathepsin B antibody [CB131]
    See all Cathepsin B primary antibodies
  • Description
    Mouse monoclonal [CB131] to Cathepsin B
  • Tested applicationsSuitable for: IHC-Pmore details
    Unsuitable for: IHC-Fr or WB
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein (Human)

  • Positive control
    • IHC: skin

Properties

Applications

Our Abpromise guarantee covers the use of ab26395 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/40 - 1/80. This product does not require protein digestion pre-treatment or antigen retrieval using heat treatment prior to staining.

    Is unsuitable for IHC-Fr or WB.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionThiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
    • Sequence similaritiesBelongs to the peptidase C1 family.
    • Cellular localizationLysosome. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    • Information by UniProt
    • Database links
    • Alternative names
      • Amyloid precursor protein secretase antibody
      • APP secretase antibody
      • APPS antibody
      • CATB_HUMAN antibody
      • Cathepsin B heavy chain antibody
      • Cathepsin B1 antibody
      • CathepsinB antibody
      • CPSB antibody
      • CTSB antibody
      • cysteine protease antibody
      • OTTHUMP00000116009 antibody
      • OTTHUMP00000229510 antibody
      • OTTHUMP00000229511 antibody
      • OTTHUMP00000229512 antibody
      • OTTHUMP00000229514 antibody
      • OTTHUMP00000229515 antibody
      • OTTHUMP00000229516 antibody
      • Preprocathepsin B antibody
      see all

    References for Anti-Cathepsin B antibody [CB131] (ab26395)

    This product has been referenced in:
    • Tizon B  et al. Cystatin C protects neuronal cells from amyloid-beta-induced toxicity. J Alzheimers Dis 19:885-94 (2010). Read more (PubMed: 20157244) »
    • van Dekken H  et al. Array comparative genomic hybridization, expression array, and protein analysis of critical regions on chromosome arms 1q, 7q, and 8p in adenocarcinomas of the gastroesophageal junction. Cancer Genet Cytogenet 189:37-42 (2009). Read more (PubMed: 19167610) »

    See all 3 Publications for this product

    Product Wall

    Thank you for forwarding the complaint form for the cathepsin B antibody. I am sorry to see that the customer has spent so much time trying to get the antibody to work.

    I think the protocol the customer used is generally correct but I am con...

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    Thank you for your enquiry. Information from our source indicates the immunogen for ab26395 Cathepsin B antibody [CB131] corresponds to the mature form of the peptide. Based on this, I believe the antibody should be able to detect both the pro and ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"