Overview

  • Product nameAnti-Cathepsin E antibody
    See all Cathepsin E primary antibodies
  • Description
    Mouse polyclonal to Cathepsin E
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 18 - 397 of Human Cathepsin E

  • Positive control
    • Stomach lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab89414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 43 kDa.

Target

  • FunctionMay have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.
  • Tissue specificityExpressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. Not expressed in resting B-lymphocytes.
  • Sequence similaritiesBelongs to the peptidase A1 family.
  • Post-translational
    modifications
    Glycosylated. The nature of the carbohydrate chain varies between cell types. In fibroblasts, the proenzyme contains a high mannose-type oligosaccharide, while the mature enzyme contains a complex-type oligosaccharide. In erythrocyte membranes, both the proenzyme and mature enzyme contain a complex-type oligosaccharide.
    Two forms are produced by autocatalytic cleavage, form I begins at Ile-54, form II begins at Thr-57.
  • Cellular localizationEndosome. The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome.
  • Information by UniProt
  • Database links
  • Alternative names
    • CATE antibody
    • CATE_HUMAN antibody
    • Cathepsin E antibody
    • Cathepsin E form II antibody
    • CTSE antibody
    • Erythrocyte membrane aspartic proteinase antibody
    • Slow moving proteinase antibody
    see all

Anti-Cathepsin E antibody images

  • Anti-Cathepsin E antibody (ab89414) at 1 µg/ml + Human stomach lysate at 50 µg

    Predicted band size : 43 kDa
  • All lanes : Anti-Cathepsin E antibody (ab89414) at 1 µg/ml

    Lane 1 : Cathepsin E transfected 293T cell lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 43 kDa
    Observed band size : 43 kDa

References for Anti-Cathepsin E antibody (ab89414)

ab89414 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab89414.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"