Anti-Cathepsin G antibody (ab197354)
Key features and details
- Rabbit polyclonal to Cathepsin G
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-Cathepsin G antibody
See all Cathepsin G primary antibodies -
Description
Rabbit polyclonal to Cathepsin G -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Recombinant fragment corresponding to Human Cathepsin G (internal sequence).
Database link: P08311 -
Positive control
- Mouse brain tissue lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Assay kits
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab197354 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (1) |
1/500 - 1/2000. Predicted molecular weight: 29 kDa.
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Notes |
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WB
1/500 - 1/2000. Predicted molecular weight: 29 kDa. |
Target
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Function
Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe-CH2Cl and phenylmethylsulfonyl fluoride. -
Sequence similarities
Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain. -
Cellular localization
Cell surface. - Information by UniProt
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Database links
- Entrez Gene: 13035 Mouse
- SwissProt: P28293 Mouse
- Unigene: 4858 Mouse
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Alternative names
- CATG antibody
- CATG_HUMAN antibody
- Cathepsin G antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (8)
ab197354 has been referenced in 8 publications.
- Featherston T et al. Cancer Stem Cells in Head and Neck Cutaneous Squamous Cell Carcinoma Express Cathepsins. Plast Reconstr Surg Glob Open 8:e3042 (2020). PubMed: 32983794
- Yang W et al. Proteomic analysis reveals a protective role of specific macrophage subsets in liver repair. Sci Rep 9:2953 (2019). PubMed: 30814596
- Rahman RMA et al. Expression of Cathepsins B, D, and G in WHO Grade I Meningioma. Front Surg 6:6 (2019). PubMed: 30949483
- Rehm SRT et al. Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation. Sci Rep 9:9925 (2019). PubMed: 31289357
- Gonzalez AA et al. Potassium Intake Prevents the Induction of the Renin-Angiotensin System and Increases Medullary ACE2 and COX-2 in the Kidneys of Angiotensin II-Dependent Hypertensive Rats. Front Pharmacol 10:1212 (2019). PubMed: 31680980
- Sionov RV et al. Neutrophil Cathepsin G and Tumor Cell RAGE Facilitate Neutrophil Anti-Tumor Cytotoxicity. Oncoimmunology 8:e1624129 (2019). PubMed: 31428521
- Tan K et al. Expression and Localization of Cathepsins B, D, and G in Dupuytren's Disease. Plast Reconstr Surg Glob Open 6:e1686 (2018). PubMed: 29616179
- Mehrotra S et al. Expression and Localization of Cathepsins B, D and G in Cancer Stem Cells in Liver Metastasis From Colon Adenocarcinoma. Front Surg 5:40 (2018). PubMed: 30177970