Anti-Cathepsin G antibody (ab49854)
Key features and details
- Rabbit polyclonal to Cathepsin G
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Cathepsin G antibody
See all Cathepsin G primary antibodies -
Description
Rabbit polyclonal to Cathepsin G -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
A synthetic peptide based on the propeptide domain and the N terminus of active human cathepsin G
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: PBS, 50% Glycerol, 2.9% Sodium chloride -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab49854 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Notes |
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Target
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Function
Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe-CH2Cl and phenylmethylsulfonyl fluoride. -
Sequence similarities
Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain. -
Cellular localization
Cell surface. - Information by UniProt
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Database links
- Entrez Gene: 1511 Human
- Omim: 116830 Human
- SwissProt: P08311 Human
- Unigene: 421724 Human
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Alternative names
- CATG antibody
- CATG_HUMAN antibody
- Cathepsin G antibody
see all
Images
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All lanes : Anti-Cathepsin G antibody (ab49854) at 1/1000 dilution
Lane 1 : Human Cathepsin G at 0.01 µg
Lane 2 : Human Cathepsin G at 0.005 µg
Lane 3 : Human Cathepsin G at 0.002 µg
Predicted band size: 29 kDa
Observed band size: 24,25,29 kDa why is the actual band size different from the predicted?
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab49854 has been referenced in 2 publications.
- Arastu-Kapur S et al. Nonproteasomal targets of the proteasome inhibitors bortezomib and carfilzomib: a link to clinical adverse events. Clin Cancer Res 17:2734-43 (2011). WB ; Human . PubMed: 21364033
- Dabek M et al. Luminal cathepsin g and protease-activated receptor 4: a duet involved in alterations of the colonic epithelial barrier in ulcerative colitis. Am J Pathol 175:207-14 (2009). WB ; Human . PubMed: 19528350