Anti-Cathepsin L/MEP antibody (ab58991)
Key features and details
- Rabbit polyclonal to Cathepsin L/MEP
- Suitable for: WB
- Reacts with: Caenorhabditis elegans
- Isotype: IgG
Overview
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Product name
Anti-Cathepsin L/MEP antibody
See all Cathepsin L/MEP primary antibodies -
Description
Rabbit polyclonal to Cathepsin L/MEP -
Host species
Rabbit -
Specificity
Reacts specifically with Cathepsin L/MEP protease 36 kDa wild type protein of C.elegans -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Caenorhabditis elegans -
Immunogen
Synthetic peptide corresponding to Caenorhabditis elegans Cathepsin L/MEP. Derived from the mature region of Cathepsin L/MEP (Caenorhabditis elegans)
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Constituent: Whole serum -
Concentration information loading...
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Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Assay kits
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab58991 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (3) |
1/200 - 1/1000. Predicted molecular weight: 38 kDa.
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Notes |
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WB
1/200 - 1/1000. Predicted molecular weight: 38 kDa. |
Target
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Function
Important for the overall degradation of proteins in lysosomes. -
Sequence similarities
Belongs to the peptidase C1 family. -
Cellular localization
Lysosome. - Information by UniProt
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Alternative names
- Cathepsin L antibody
- cathepsin L, 1 b antibody
- Cathepsin L1 antibody
see all
Protocols
Datasheets and documents
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Datasheet download
References (28)
ab58991 has been referenced in 28 publications.
- Xu L et al. ER-mitochondrial contact protein Miga regulates autophagy through Atg14 and Uvrag. Cell Rep 41:111583 (2022). PubMed: 36323251
- Takáts S et al. The Warburg Micro Syndrome-associated Rab3GAP-Rab18 module promotes autolysosome maturation through the Vps34 Complex I. FEBS J 288:190-211 (2021). PubMed: 32248620
- Laczkó-Dobos H et al. Lipid profiles of autophagic structures isolated from wild type and Atg2 mutant Drosophila. Biochim Biophys Acta Mol Cell Biol Lipids 1866:158868 (2021). PubMed: 33333179
- Lakatos Z et al. Drosophila Rab39 Attenuates Lysosomal Degradation. Int J Mol Sci 22:N/A (2021). PubMed: 34638976
- Jacomin AC et al. Regulation of Expression of Autophagy Genes by Atg8a-Interacting Partners Sequoia, YL-1, and Sir2 in Drosophila. Cell Rep 31:107695 (2020). PubMed: 32460019