Anti-Cathepsin S antibody (ab103848)

Overview

• Product name
  Anti-Cathepsin S antibody
  See all Cathepsin S primary antibodies
• Description
  Rabbit polyclonal to Cathepsin S
• Tested applications
  Suitable for: WBmore details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Synthetic peptide conjugated to KLH derived from within residues 300 to the C-terminus of Human Cathepsin S.

  Read Abcam's proprietary immunogen policy

• Positive control
  • This antibody gave a positive signal in the following lysates: Lung (Human) Tissue Lysate; Spleen (Human) Tissue Lysate - adult normal tissue;

Properties

• Form
  Liquid
• Storage instructions
  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• Storage buffer
  Preservative: 0.02% Sodium Azide
  Constituents: 1% BSA, PBS, pH 7.4
• Concentration information loading...
• Purity
  Immunogen affinity purified
• Clonality
  Polyclonal
• Isotype
  IgG
• Research areas
  • Immunology
  • Adaptive Immunity
  • MHC
  • Class II

  • Tags & Cell Markers
  • Subcellular Markers
  • Organelles
  • Lysosome

  • Immunology
  • Cell Type Markers
  • Non-CD
  • APC

  • Cell Biology
  • Proteolysis / Ubiquitin
  • Proteolytic enzymes

  • Cell Biology
  • Proteolysis / Ubiquitin
  • Proteolytic enzymes
  • Cysteine protease
  • Cathepsins

Associated products

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

Applications

Target

• Function
  Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
• Sequence similarities
  Belongs to the peptidase C1 family.
• Cellular localization
  Lysosome.

• Target information above from: UniProt accession P25774 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 1520 Human
  • Omim: 116845 Human
  • SwissProt: P25774 Human
  • Unigene: 181301 Human
• Alternative names
  • Cathepsin S antibody
  • CathepsinS antibody
  • CATS_HUMAN antibody
  • Ctss antibody

Protocols

• Western blot protocols