Overview

  • Product name
    Anti-Cathepsin S antibody
    See all Cathepsin S primary antibodies
  • Description
    Rabbit polyclonal to Cathepsin S
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 300 to the C-terminus of Human Cathepsin S.

    Read Abcam's proprietary immunogen policy

  • Positive control
    • This antibody gave a positive signal in the following lysates: Lung (Human) Tissue Lysate; Spleen (Human) Tissue Lysate - adult normal tissue;

Properties

Applications

Our Abpromise guarantee covers the use of ab103848 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 mg/ml. Detects a band of approximately 25 kDa (predicted molecular weight: 37 kDa).

Target

  • Function
    Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
  • Sequence similarities
    Belongs to the peptidase C1 family.
  • Cellular localization
    Lysosome.
  • Information by UniProt
  • Database links
    • Alternative names
      • Cathepsin S antibody
      • CathepsinS antibody
      • CATS_HUMAN antibody
      • Ctss antibody

    Images

    • Western blot - Anti-Cathepsin S antibody (ab103848)
      Western blot - Anti-Cathepsin S antibody (ab103848)
      All lanes : Anti-Cathepsin S antibody (ab103848) at 1 µg/ml

      Lane 1 : Lung (Human) Tissue Lysate
      Lane 2 : Human spleen tissue lysate - total protein (ab29699)

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed at 1/5000 dilution

      Developed using the ECL technique.

      Performed under reducing conditions.

      Predicted band size: 37 kDa
      Observed band size: 25 kDa (why is the actual band size different from the predicted?)


      Exposure time: 20 minutes


      We hypothesize that the 25 kDa band represents the mature form of Cathepsin S. Abcam welcomes customer feedback.

    References

    ab103848 has not yet been referenced specifically in any publications.

    Publishing research using ab103848? Please let us know so that we can cite the reference in this datasheet.

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