Anti-Cathepsin W antibody [BV39-2B] (ab24529)

Overview

  • Product name
    Anti-Cathepsin W antibody [BV39-2B]
    See all Cathepsin W primary antibodies
  • Description
    Mouse monoclonal [BV39-2B] to Cathepsin W
  • Specificity
    This antibody recognises Cathepsin W and Procathepsin W, but no other Cathepsins.
  • Tested applications
    Suitable for: WB, IHC-Frmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant human ProCathepsin W.

Properties

Applications

Our Abpromise guarantee covers the use of ab24529 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 4 µg/ml. Predicted molecular weight: 42 kDa.
IHC-Fr Use a concentration of 20 - 30 µg/ml.

Target

  • Function
    Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation.
  • Tissue specificity
    Predominantly expressed in osteoclasts (bones).
  • Involvement in disease
    Pycnodysostosis
  • Sequence similarities
    Belongs to the peptidase C1 family.
  • Cellular localization
    Lysosome.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cathepsin K antibody
    • Cathepsin O antibody
    • Cathepsin O2 antibody
    • Cathepsin X antibody
    • CATK_HUMAN antibody
    • Ctsk antibody
    • CTSW antibody
    • Lymphopain antibody
    • LYPN antibody
    see all

References

ab24529 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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