• Product nameAnti-CatSper2 antibody
    See all CatSper2 primary antibodies
  • Description
    Rabbit polyclonal to CatSper2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    A region within synthetic peptide: MEMDQDDRVW PRDSLFRYFE LLEKLQYNLE ERKKLQEFAV QALMNLEDK, corresponding to C terminal amino acids 482-530 of Human CatSper2

  • Positive control
    • HepG2 cell lysate.



Our Abpromise guarantee covers the use of ab66642 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 58 kDa (predicted molecular weight: 62 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • RelevanceCatSper2 belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. Calcium ions play a primary role in the regulation of sperm motility. The protein family features a single repeat with six membrane spanning segments and a predicted calcium selective pore region. A second, closely linked copy of the gene has been identified. Although multiple transcript variants encoding protein isoforms have been characterized, they seem to be only transcribed from this gene. Additional splice variants have been described but their full length nature has not been determined.
  • Cellular localizationCell projection, cilium, flagellum; Multi-pass membrane protein
  • Database links
  • Alternative names
    • Cation channel sperm associated 2 antibody
    • Cation channel sperm associated protein 2 antibody
    • Catsper 2 antibody
    • MGC33346 antibody
    • Putative ion channel protein CATSPER2 variant 1 antibody
    • Putative ion channel protein CATSPER2 variant 2 antibody
    • Putative ion channel protein CATSPER2 variant 3 antibody
    • Sperm associated cation channel 2 antibody
    • Sperm ion channel antibody
    see all

Anti-CatSper2 antibody images

  • All lanes : Anti-CatSper2 antibody (ab66642) at 1.25 µg/ml

    Lane 1 : Molecular weight markers
    Lane 2 : HepG2 cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 62 kDa
    Observed band size : 58 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 47 kDa. We are unsure as to the identity of these extra bands.

References for Anti-CatSper2 antibody (ab66642)

ab66642 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your reply.

I have contacted the lab and asked for specific identity percentages for ab101891, ab101894 and ab101895 as requested. I will let you know as soon as I receive those.

Regarding our Abreview 100% testing...

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Thank you for contacting us.

I have received some information about our CATSPER1,CATSPER2 and CATSPER3 antibodies. The immunogens against which these products have been created did not so any significant identity with the mouse proteins. W...

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Yes of course. We are also awaiting the reply from our supplier and will follow up with them early next month if we do not hear from them sooner. We will forward you any information regarding the immunogen sequence as soon as we get it.

Thanks for letting me know you have already received a replacement. Best of luck in your research.

So glad to hear you liked the brownies!

When you have a chance, please let me knowif you would like thefree replacement antibody and I'll be happy to send it along.

Havea great weekend!

I understand your frustration with the lack of information here. I am sorry but with this particular academic source of ab43259, there is only one person we have on record (the PI) who remains in the lab from when the antibody was produced. <...

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Thank you for your reply.

Yes, I have passed on your comments and concerns last Fridayto the lab where we source the antibody ab43259 from. As of now I have not yet hear back from them, thus, do not have further information yet. Yes, Iunders...

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