Human Predicted to work with:
Mouse, Rat, Chicken
Recombinant fragment: HVNTDRECPL FGLSGINASS VPTDGSGPSM HPSELIAEMR NSGFALKRNV LGRNLTANDP SQEYVASEG, corresponding to amino acids 136-205 of Human CBF1 interacting corepressor (NP_004873) with a 26kDa tag
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 52 kDa.
Use at an assay dependent dilution.
RelevanceCBF1 interacting corepressor may modulate splice site selection during alternative splicing of pre-mRNAs. It regulates transcription and acts as corepressor for RBPSUH; recruits RBPSUH to the Sin3-histone deacetylase complex (HDAC).