Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab91185 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-Fr
ICC/IF
  • Application notes
    ICC/IF: 1/50.
    IHC-Fr: 1/50.
    WB: 1/50. Predicted molecular weight: 55 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Promotes ubiquitination of tyrosine-phosphorylated CDH1, thus targeting CDH1 for endocytosis and degradation.
    • Pathway
      Protein modification; protein ubiquitination.
    • Sequence similarities
      Contains 1 C2H2-type zinc finger.
      Contains 1 RING-type zinc finger.
    • Information by UniProt
    • Database links
    • Alternative names
      • c-Cbl-like protein 1 antibody
      • CasBrM (murine) ecotropic retroviral transforming sequencelike 1 antibody
      • Casitas B-lineage lymphoma transforming sequence-like protein 1 antibody
      • Casitas B-lineage lymphoma-like 1 antibody
      • Casitas B-lineage lymphoma-transforming sequence-like protein 1 antibody
      • cbll1 antibody
      • E3 ubiquitin-protein ligase Hakai antibody
      • Ecadherin binding protein E7 antibody
      • FLJ23109 antibody
      • HAKAI antibody
      • HAKAI_HUMAN antibody
      • MGC163401 antibody
      • MGC163403 antibody
      • OTTHUMP00000206720 antibody
      • OTTHUMP00000206722 antibody
      • OTTHUMP00000206724 antibody
      • RING finger protein 188 antibody
      • RNF188 antibody
      see all

    References

    This product has been referenced in:
    • Zhou WJ  et al. Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis. Cell Res 21:609-26 (2011). Read more (PubMed: 21283129) »

    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab91185.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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