Overview

  • Product nameAnti-CBR1 antibody (HRP)
    See all CBR1 primary antibodies
  • Description
    Goat polyclonal to CBR1 (HRP)
  • ConjugationHRP
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    C-HGQFVSEKRVEQW

    , corresponding to C terminal amino acids 265-277 of Human CBR1 according to NP_001748.1.

  • Positive control
    • Human liver lysates.
  • General notes

    Conjugated via amine groups to horseradish peroxidise.

Properties

Applications

Our Abpromise guarantee covers the use of ab124170 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 30 kDa.

Target

  • FunctionNADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
  • Sequence similaritiesBelongs to the short-chain dehydrogenases/reductases (SDR) family.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • 15 hydroxyprostaglandin dehydrogenase [NADP+] antibody
    • 15-hydroxyprostaglandin dehydrogenase [NADP+] antibody
    • Carbonyl reductase [NADPH] 1 antibody
    • Carbonyl Reductase 1 antibody
    • CBR 1 antibody
    • CBR1 antibody
    • CBR1_HUMAN antibody
    • CRN antibody
    • NADPH dependent carbonyl reductase 1 antibody
    • NADPH-dependent carbonyl reductase 1 antibody
    • Prostaglandin 9 ketoreductase antibody
    • Prostaglandin 9-ketoreductase antibody
    • Prostaglandin E(2) 9 reductase antibody
    • Prostaglandin-E(2) 9-reductase antibody
    • SDR21C1 antibody
    see all

Anti-CBR1 antibody (HRP) images

  • Anti-CBR1 antibody (HRP) (ab124170) at 1/1000 dilution + Human liver lysates in RIPA buffer at 35 µg

    Predicted band size : 30 kDa

References for Anti-CBR1 antibody (HRP) (ab124170)

ab124170 has not yet been referenced specifically in any publications.

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