Overview

  • Product nameAnti-CBR4 antibody
    See all CBR4 primary antibodies
  • Description
    Rabbit polyclonal to CBR4
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Rabbit, Guinea pig, Cow, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 156-205 (VGFSRALAKE VARKKIRVNV VAPGFVHTDM TKDLKEEHLK KNIPLGRFGE) of Human CBR4 (NP_116172).

  • Positive control
    • Jurkat cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab115860 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionThe heteroteramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro).
  • Tissue specificityDetected in liver and kidney (at protein level).
  • PathwayLipid metabolism; fatty acid biosynthesis.
  • Sequence similaritiesBelongs to the short-chain dehydrogenases/reductases (SDR) family.
  • Cellular localizationMitochondrion matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • 3 oxoacyl [acyl carrier protein] reductase antibody
    • 3-oxoacyl-[acyl-carrier-protein] reductase antibody
    • Carbonic reductase 4 antibody
    • Carbonyl reductase 4 antibody
    • Carbonyl reductase family member 4 antibody
    • CBR 4 antibody
    • Cbr4 antibody
    • CBR4_HUMAN antibody
    • FLJ14431 antibody
    • Quinone reductase CBR4 antibody
    • SDR45C1 antibody
    • Short chain dehydrogenase/reductase family 45C member 1 antibody
    see all

Anti-CBR4 antibody images

  • Anti-CBR4 antibody (ab115860) at 1 µg/ml + Jurkat cell lysate at 10 µg

    Predicted band size : 25 kDa

References for Anti-CBR4 antibody (ab115860)

ab115860 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Human Recombinant protein (Human rCBR4)
Loading amount 0.03 µg
Specification Human rCBR4
Gel Running Conditions Non-reduced Denaturing (12% Tris/glycine gel)
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
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Submitted Nov 14 2012

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"