Overview

  • Product nameAnti-CBX1 / HP1 beta antibodySee all CBX1 / HP1 beta primary antibodies ...
  • Description
    Rabbit polyclonal to CBX1 / HP1 beta
  • Tested applicationsELISA, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide from the N-terminal region of human CBX4, conjugated to KLH

  • Positive control
    • Mouse kidney lysate; Human hepatocarcinoma tissue.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesThe antibody was purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
  • Clonality Polyclonal
  • IsotypeIgG
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab71635 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/100 - 1/500. Predicted molecular weight: 61 kDa.
IHC-P 1/50 - 1/100.

Target

  • FunctionComponent of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
  • Tissue specificityExpressed in all adult and embryonic tissues.
  • Sequence similaritiesContains 2 chromo domains.
  • Post-translational
    modifications
    Not phosphorylated.
    Ubiquitinated.
  • Cellular localizationNucleus. Unassociated with chromosomes during mitosis.
  • Information by UniProt
  • Database links
  • Alternative names
    • CBX 1 antibody
    • CBX antibody
    • Cbx1 antibody
    • CBX1_HUMAN antibody
    • chromobox homolog 1 antibody
    • Chromobox protein homolog 1 antibody
    • Drosophila HP1 beta antibody
    • Heterochromatin protein 1 beta antibody
    • Heterochromatin protein 1 homolog beta antibody
    • Heterochromatin protein p25 antibody
    • heterochromatin protein p25 beta antibody
    • HP1 beta antibody
    • HP1 beta homolog antibody
    • HP1 beta homolog Drosophila antibody
    • HP1beta antibody
    • HP1Hs beta antibody
    • HP1Hsbeta antibody
    • Human heterochromatin protein p25 mRNA complete cds antibody
    • M31 antibody
    • MOD 1 antibody
    • MOD1 antibody
    • Modifier 1 protein antibody
    • p25beta antibody
    see all

Anti-CBX1 / HP1 beta antibody images

  • Anti-CBX1 / HP1 beta antibody (ab71635) at 1/100 dilution + Mouse kidney tissue lysate at 12.5 µg

    Predicted band size : 61 kDa
    Observed band size : 61 kDa
    Additional bands at : 25 kDa,36 kDa,45 kDa. We are unsure as to the identity of these extra bands.
  • Analysis of CBX4 expression on formalin-fixed and paraffin-embedded human hepatocarcinoma tissue using ab71635 at 1:50 dilution (peroxidase conjugation secondary antibody, AEC staining).

References for Anti-CBX1 / HP1 beta antibody (ab71635)

ab71635 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"