The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 25 kDa (predicted molecular weight: 21 kDa).
Use a concentration of 2 - 3 µg/ml.
FunctionComponent of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
Tissue specificityExpressed in all adult and embryonic tissues.
ab40828 at 2.5µg/ml staining CBX1 / HP1 in human placenta tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections). Tissue underwent antigen retrieval in steam with citrate buffer (pH 6.0). The AP-staining procedure was used for detection.
References for Anti-CBX1 / HP1 beta antibody (ab40828)
has not yet been referenced specifically in any publications.
Publishing research using ab40828? Please let us know so that we can cite the reference in this datasheet.
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