Overview

  • Product nameAnti-CC2D1A antibody
    See all CC2D1A primary antibodies
  • Description
    Rabbit polyclonal to CC2D1A
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 142-172 of Human CC2D1A (NP_060191.3).

  • Positive control
    • K562 cell line lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab123590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 104 kDa.

Target

  • RelevanceCC2D1A belongs to the CC2D1 family. It contains one C2 domain. It is a transcription factor that binds specifically to the FRE (five repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. CC2D1A may play a role in the altered regulation of HTR1A associated with anxiety and major depression. It also mediates HDAC-independent repression of HTR1A promoter in neuronal cell. There are three named isoforms. Defects in CC2D1A are the cause of non-syndromic mental retardation autosomal recessive type 3 (MRT3). Patients display severe mental retardation and psychomotor development delay in early childhood. Non-syndromic mental retardation patients do not manifest other clinical signs.
  • Cellular localizationCytoplasm. Nucleus.
  • Database links
  • Alternative names
    • Akt kinase interacting protein 1 antibody
    • Coiled coil and C2 domain containing 1A antibody
    • Coiled coil and C2 domain containing protein 1A antibody
    • Five repressor element under dual repression binding protein 1 antibody
    • FLJ20241 antibody
    • FLJ41160 antibody
    • FRE under dual repression binding protein 1 antibody
    • FREUD 1 antibody
    • Freud 1/Aki1 antibody
    • Mental retardation, nonsyndromic, autosomal recessive, 3 antibody
    • MRT3 antibody
    • Putative NF kappa B activating protein 023N antibody
    • Putative NF kappa B activating protein antibody
    see all

Anti-CC2D1A antibody images

  • Anti-CC2D1A antibody (ab123590) at 1/100 dilution + K562 cell line lysate at 35 µg

    Predicted band size : 104 kDa

References for Anti-CC2D1A antibody (ab123590)

ab123590 has not yet been referenced specifically in any publications.

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