Overview

  • Product nameAnti-CCBE1 antibody
    See all CCBE1 primary antibodies
  • Description
    Rabbit polyclonal to CCBE1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human, Zebrafish
    Predicted to work with: Mouse, Rat, Rabbit, Chicken, Guinea pig, Cow, Cat, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within the internal sequence amino acids 287-336 (PMGPSPDLSH IKQGRRGPVG PPGAPGRDGS KGERGAPGPR GSPGPPGSFD) of Human CCBE1 (NP_597716).

  • Positive control
    • ACHN cell lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab101967 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 44 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionRequired for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis.
  • Tissue specificityNot expressed in blood or lymphatic endothelial cells.
  • Involvement in diseaseDefects in CCBE1 are the cause of Hennekam lymphangiectasia-lymphedema syndrome (HLYLMP) [MIM:235510]. HLYLMP is a generalized lymph-vessels dysplasia characterized by intestinal lymphangiectasia with severe lymphedema of the limbs, genitalia and face. In addition, affected individuals have unusual facies and severe mental retardation.
  • Sequence similaritiesBelongs to the CCBE1 family.
    Contains 2 collagen-like domains.
    Contains 1 EGF-like domain.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • CCBE 1 antibody
    • ccbe1 antibody
    • CCBE1_HUMAN antibody
    • Collagen and calcium binding EGF domain containing protein 1 antibody
    • Collagen and calcium binding EGF domains 1 antibody
    • Collagen and calcium-binding EGF domain-containing protein 1 antibody
    • FLJ30681 antibody
    • Full of fluid protein homolog antibody
    • MGC50861 antibody
    see all

Anti-CCBE1 antibody images

  • Anti-CCBE1 antibody (ab101967) at 1 µg/ml + ACHN cell lysate at 10 µg

    Predicted band size : 44 kDa

References for Anti-CCBE1 antibody (ab101967)

This product has been referenced in:
  • Le Guen L  et al. Ccbe1 regulates Vegfc-mediated induction of Vegfr3 signaling during embryonic lymphangiogenesis. Development 141:1239-49 (2014). WB ; Zebrafish . Read more (PubMed: 24523457) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab101967.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"