Anti-CCBL1 antibody - C-terminal (ab174543)

Overview

  • Product name
    Anti-CCBL1 antibody - C-terminal
    See all CCBL1 primary antibodies
  • Description
    Rabbit polyclonal to CCBL1 - C-terminal
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human CCBL1 aa 326-355 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q16773

  • Positive control
    • MDA-MB453 cell line lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab174543 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 48 kDa.

Target

  • Relevance
    CCBL1 is a cytosolic enzyme which is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism leads to the formation of reactive metabolites which can lead to nephrotoxicity and neurotoxicity. CCBL1 catalyzes the irreversible transamination of the L-tryptophan metabolite L-kinurenine to form kynurenic acid (KA). It catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. This enzyme has a central role in the bioactivation of nephrotoxic halogenated hydrocarbons - the possibility of human exposure to these chemicals has focused interest on the CCBL1 from human kidney.
  • Cellular localization
    Cytoplasmic
  • Database links
  • Alternative names
    • Beta lyase antibody
    • Beta lysase, kidney antibody
    • CCBL 1 antibody
    • Cysteine conjugate beta lyase antibody
    • Cysteine conjugate beta lyase, cytoplasmic antibody
    • Cysteine conjugate beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) antibody
    • Cysteine S conjugate beta lyase antibody
    • Cytoplasmic cysteine conjugate beta lyase antibody
    • FLJ95217 antibody
    • Glutamine phenylpyruvate aminotransferase antibody
    • Glutamine transaminase K antibody
    • GTK antibody
    • KAT1 antibody
    • KATI antibody
    • Kyneurenine aminotransferase antibody
    • Kynurenine aminotransferase I antibody
    • Kynurenine oxoglutarate transaminase 1 antibody
    • MGC29624 antibody
    • OTTHUMP00000022311 antibody
    • OTTHUMP00000022312 antibody
    see all

Images

  • Anti-CCBL1 antibody - C-terminal (ab174543) at 1/100 dilution + MDA-MB453 cell line lysate at 35 µg

    Predicted band size : 48 kDa

References

ab174543 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab174543.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up