Overview

  • Product nameAnti-CCDC50 antibody
    See all CCDC50 primary antibodies
  • Description
    Rabbit polyclonal to CCDC50
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region between residue 225 and 275 of Human CCDC50 (NP_777568.1).

  • Positive control
    • Human breast carcinoma, osteosarcoma, ovarian carcinoma and stomach adenocarcinoma

Properties

Applications

Our Abpromise guarantee covers the use of ab101287 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

Target

  • FunctionInvolved in EGFR signaling.
  • Tissue specificityIsoform 1 and isoform 2 are co-expressed in placenta, liver, lung, kidney and pancreas. Only isoform 1 is detected in skeletal muscle, brain and heart.
  • Involvement in diseaseDefects in CCDC50 are the cause of deafness autosomal dominant type 44 (DFNA44) [MIM:607453]. A form of non-syndromic hearing loss. It is initially moderate and affects mainly low to mid frequencies. Later, it progresses to involve all the frequencies and leads to a profound hearing loss by the 6th decade. The onset of the hearing loss occurs in the first decade of life.
  • Post-translational
    modifications
    Phosphorylated on tyrosine residues.
  • Cellular localizationCytoplasm. Associated with microtubules of the cytoskeleton and mitotic apparatus.
  • Information by UniProt
  • Database links
  • Alternative names
    • C3orf6 antibody
    • C3orf6 YMER antibody
    • CCD50_HUMAN antibody
    • CCDC 50 antibody
    • Ccdc50 antibody
    • Chromosome 3 open reading frame 6 antibody
    • Coiled coil domain containing 50 antibody
    • Coiled coil domain containing protein 50 antibody
    • Coiled-coil domain-containing protein 50 antibody
    • Protein Ymer antibody
    • Ymer antibody
    • Ymer protein antibody
    see all

Anti-CCDC50 antibody images

  • ab101287, at 1/250 dilution, staining CCDC50 in formalin-fixed paraffin-embedded Human ovarian carcinoma by Immunohistochemistry using DAB staining.

References for Anti-CCDC50 antibody (ab101287)

ab101287 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab101287.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"