Overview

  • Product name
  • Description
    Goat polyclonal to CCDC50
  • Specificity
    This antibody is expected to recognise both reported isoforms of human CCDC50 protein.
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Chimpanzee
  • Immunogen

    Synthetic peptide:

    (C)FSKSESSHKGFHYK

    , corresponding to C terminal amino acids 292-305 of Human CCDC50

Properties

Applications

Our Abpromise guarantee covers the use of ab32884 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notes
    IHC-P: Use at a concentration of 5 µg/ml.
    This antibody gave a positive result in ELISA against the immunizing peptide. Antibody detection limit dilution 1:32,000.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Involved in EGFR signaling.
    • Tissue specificity
      Isoform 1 and isoform 2 are co-expressed in placenta, liver, lung, kidney and pancreas. Only isoform 1 is detected in skeletal muscle, brain and heart.
    • Involvement in disease
      Defects in CCDC50 are the cause of deafness autosomal dominant type 44 (DFNA44) [MIM:607453]. A form of non-syndromic hearing loss. It is initially moderate and affects mainly low to mid frequencies. Later, it progresses to involve all the frequencies and leads to a profound hearing loss by the 6th decade. The onset of the hearing loss occurs in the first decade of life.
    • Post-translational
      modifications
      Phosphorylated on tyrosine residues.
    • Cellular localization
      Cytoplasm. Associated with microtubules of the cytoskeleton and mitotic apparatus.
    • Information by UniProt
    • Database links
    • Alternative names
      • C3orf6 antibody
      • C3orf6 YMER antibody
      • CCD50_HUMAN antibody
      • CCDC 50 antibody
      • Ccdc50 antibody
      • Chromosome 3 open reading frame 6 antibody
      • Coiled coil domain containing 50 antibody
      • Coiled coil domain containing protein 50 antibody
      • Coiled-coil domain-containing protein 50 antibody
      • Protein Ymer antibody
      • Ymer antibody
      • Ymer protein antibody
      see all

    Anti-CCDC50 antibody images

    • ab32884 at 5ug/ml staining CCDC50 in human pancreas tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections). Tissue underwent antigen retrieval in steam with citrate buffer (pH 6.0). A AP-staining procedure was used for detection.

    References for Anti-CCDC50 antibody (ab32884)

    ab32884 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab32884.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up