Overview

  • Product name
    CCDC50 peptide (292-305)

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-FSKSESSHKGFHYK
    • Amino acids
      292 to 305

Associated products

Specifications

Our Abpromise guarantee covers the use of ab45644 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-CCDC50 antibody (ab32884)

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • C3orf6
    • C3orf6 YMER
    • CCD50_HUMAN
    • CCDC 50
    • Ccdc50
    • Chromosome 3 open reading frame 6
    • Coiled coil domain containing 50
    • Coiled coil domain containing protein 50
    • Coiled-coil domain-containing protein 50
    • Protein Ymer
    • Ymer
    • Ymer protein
    see all
  • Function
    Involved in EGFR signaling.
  • Tissue specificity
    Isoform 1 and isoform 2 are co-expressed in placenta, liver, lung, kidney and pancreas. Only isoform 1 is detected in skeletal muscle, brain and heart.
  • Involvement in disease
    Defects in CCDC50 are the cause of deafness autosomal dominant type 44 (DFNA44) [MIM:607453]. A form of non-syndromic hearing loss. It is initially moderate and affects mainly low to mid frequencies. Later, it progresses to involve all the frequencies and leads to a profound hearing loss by the 6th decade. The onset of the hearing loss occurs in the first decade of life.
  • Post-translational
    modifications
    Phosphorylated on tyrosine residues.
  • Cellular localization
    Cytoplasm. Associated with microtubules of the cytoskeleton and mitotic apparatus.
  • Information by UniProt

References

ab45644 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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