Overview

  • Product name
    Anti-CCDC53 antibody
  • Description
    Rabbit polyclonal to CCDC53
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: LMGSGIDLTK VPAIQQKRTV AFLNQFVVHT VQFLNRFSTV CEEKLADLSL RIQQIETTLN ILDAKLSSIP GLDDVTVEVS P, corresponding to amino acids 8-88 of Human CCDC53.

  • Positive control
    • Human smooth muscle tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab122461 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/20. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting.
  • Sequence similarities
    Belongs to the CCDC53 family.
  • Information by UniProt
  • Database links
  • Alternative names
    • AD-016 antibody
    • CCD53_HUMAN antibody
    • CCDC53 antibody
    • CGI-116 antibody
    • Coiled-coil domain-containing protein 53 antibody
    • WASH complex subunit CCDC53 antibody
    see all

Images

  • ab122461, at 1/10 dilution, staining CCDC53 in paraffin-embedded Human smooth muscle tissue by Immunohistochemistry.

References

ab122461 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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