Overview

  • Product name
  • Description
    Rabbit polyclonal to CCDC6
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Zebrafish
  • Immunogen

    Recombinant fragment corresponding to a region within amino acids 1-222 of Human CCDC6. (Uniprot:Q16204)

  • Positive control
    • HepG2 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab155212 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 53 kDa.

Target

  • Tissue specificity
    Ubiquitously expressed.
  • Involvement in disease
    Defects in CCDC6 are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving CCDC6 is found in thyroid papillary carcinomas. Inversion inv(10)(q11.2;q21) generates the RET/CCDC6 (PTC1) oncogene.
  • Domain
    The protein has mostly an alpha helical conformation similar to myosin heavy-chain tail that might adopt a coiled-coil conformation.
  • Cellular localization
    Cytoplasm. Cytoplasm > cytoskeleton. May be a cytoskeletal protein.
  • Information by UniProt
  • Database links
  • Alternative names
    • CCDC 6 antibody
    • CCDC6 antibody
    • CCDC6_HUMAN antibody
    • Coiled coil domain containing 6 antibody
    • Coiled coil domain containing protein 6 antibody
    • Coiled-coil domain-containing protein 6 antibody
    • D10S170 antibody
    • FLJ32286 antibody
    • H4 antibody
    • Papillary thyroid carcinoma encoded protein antibody
    • Papillary thyroid carcinoma-encoded protein antibody
    • Protein H4 antibody
    • PTC antibody
    • TPC antibody
    • TST 1 antibody
    • TST1 antibody
    see all

Images

  • Anti-CCDC6 antibody (ab155212) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 53 kDa

References

ab155212 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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