• Product nameAnti-CCDC6 antibody
    See all CCDC6 primary antibodies
  • Description
    Rabbit polyclonal to CCDC6
  • Tested applicationsSuitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Dog, Pig, Xenopus laevis, Chimpanzee, Zebrafish, Rhesus monkey, Orangutan, Xenopus tropicalis , Medaka fish
  • Immunogen

    Synthetic peptide corresponding to a region between residues 75 and 125 of Human CCDC6 (AAC60637.1).

  • Positive control
    • HeLa whole cell lysate.


Associated products


Our Abpromise guarantee covers the use of ab85923 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Predicted molecular weight: 66 kDa.
IP Use at 2-5 µg/mg of lysate.


  • Tissue specificityUbiquitously expressed.
  • Involvement in diseaseDefects in CCDC6 are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving CCDC6 is found in thyroid papillary carcinomas. Inversion inv(10)(q11.2;q21) generates the RET/CCDC6 (PTC1) oncogene.
  • DomainThe protein has mostly an alpha helical conformation similar to myosin heavy-chain tail that might adopt a coiled-coil conformation.
  • Cellular localizationCytoplasm. Cytoplasm > cytoskeleton. May be a cytoskeletal protein.
  • Information by UniProt
  • Database links
  • Alternative names
    • CCDC 6 antibody
    • CCDC6 antibody
    • CCDC6_HUMAN antibody
    • Coiled coil domain containing 6 antibody
    • Coiled coil domain containing protein 6 antibody
    • Coiled-coil domain-containing protein 6 antibody
    • D10S170 antibody
    • FLJ32286 antibody
    • H4 antibody
    • Papillary thyroid carcinoma encoded protein antibody
    • Papillary thyroid carcinoma-encoded protein antibody
    • Protein H4 antibody
    • PTC antibody
    • TPC antibody
    • TST 1 antibody
    • TST1 antibody
    see all

Anti-CCDC6 antibody images

  • All lanes : Anti-CCDC6 antibody (ab85923) at 0.1 µg/ml

    Lane 1 : HeLa whole cell lysate at 50 µg
    Lane 2 : HeLa whole cell lysate at 15 µg
    Lane 3 : HeLa whole cell lysate at 5 µg

    developed using the ECL technique

    Predicted band size : 66 kDa
    Observed band size : 70 kDa (why is the actual band size different from the predicted?)

    Exposure time : 30 seconds
  • Detection of Human CCDC6 in Immunoprecipitates of Whole cell lysate from HeLa cells (1 mg for IP, 20% of IP loaded) using ab85923 at 3 µg/mg lysate for IP and at 1 µg/ml for subsequent Western blot detection. Detection: Chemiluminescence with an exposure time of 10 seconds.

References for Anti-CCDC6 antibody (ab85923)

ab85923 has not yet been referenced specifically in any publications.

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