Overview

  • Product name
    Anti-CCDC88C antibody
  • Description
    Rabbit polyclonal to CCDC88C
  • Tested applications
    Suitable for: ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to amino acids 1571-1698 of Human CCDC88C.

  • Positive control
    • Human testis tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab121235 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. pH 6.0

Target

  • Function
    Negative regulator of the canonical Wnt signaling pathway, acting downstream of DVL to inhibit CTNNB1/Beta-catenin stabilization.
  • Sequence similarities
    Belongs to the CCDC88 family.
  • Information by UniProt
  • Database links
  • Alternative names
    • ccdc88c antibody
    • Coiled-coil domain-containing protein 88C antibody
    • DAPLE antibody
    • DAPLE_HUMAN antibody
    • Dvl-associating protein with a high frequency of leucine residues antibody
    • hDaple antibody
    • HkRP2 antibody
    • Hook-related protein 2 antibody
    • KIAA1509 antibody
    • Protein Daple antibody
    see all

Images

  • Immunofluorescent staining of Human cell line A-431 shows positivity in nucleus and nucleoli. Recommended concentration of ab121235 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • Immunohistochemical staining of paraffin embedded Human testis tissue, using 1/350 ab121235, shows strong nuclear positivity in cells of seminiferus ducts and Leydig cells.

References

ab121235 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab121235.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up