Overview

  • Product nameAnti-CCDC88C antibody
  • Description
    Rabbit polyclonal to CCDC88C
  • Tested applicationsSuitable for: ICC/IF, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to amino acids 1571-1698 of Human CCDC88C.

  • Positive control
    • Human testis tissue

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab121235 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. pH 6.0

Target

  • FunctionNegative regulator of the canonical Wnt signaling pathway, acting downstream of DVL to inhibit CTNNB1/Beta-catenin stabilization.
  • Sequence similaritiesBelongs to the CCDC88 family.
  • Information by UniProt
  • Database links
  • Alternative names
    • ccdc88c antibody
    • Coiled-coil domain-containing protein 88C antibody
    • DAPLE antibody
    • DAPLE_HUMAN antibody
    • Dvl-associating protein with a high frequency of leucine residues antibody
    • hDaple antibody
    • HkRP2 antibody
    • Hook-related protein 2 antibody
    • KIAA1509 antibody
    • Protein Daple antibody
    see all

Anti-CCDC88C antibody images

  • Immunofluorescent staining of Human cell line A-431 shows positivity in nucleus and nucleoli. Recommended concentration of ab121235 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • Immunohistochemical staining of paraffin embedded Human testis tissue, using 1/350 ab121235, shows strong nuclear positivity in cells of seminiferus ducts and Leydig cells.

References for Anti-CCDC88C antibody (ab121235)

ab121235 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab121235.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"