Overview

  • Product nameAnti-CCL14 antibody
    See all CCL14 primary antibodies
  • Description
    Mouse monoclonal to CCL14
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: TKTESSSRGP YHPSECCFTY TTYKIPRQRI MDYYETNSQC SKPGIVFITK RGHSVCTNPS DKWVQDYIKD MKEN, corresponding to amino acids 20-93 of Human CCL14

Properties

Applications

Our Abpromise guarantee covers the use of ab55752 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionHas weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induced intracellular Ca(2+) changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and was inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5.
    • Tissue specificityExpressed constitutively in several normal tissues: spleen, liver, skeletal and heart muscle, gut, and bone marrow, present at high concentrations (1-80 nM) in plasma.
    • Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
    • Post-translational
      modifications
      The N-terminal processed forms HCC-1(3-74), HCC-1(4-74) and HCC-1(9-74) are produced in small amounts by proteolytic cleavage after secretion in blood.
      HCC-1(1-74), but not HCC-1(3-74) and HCC-1(4-74), is partially O-glycosylated; the O-linked glycan consists of one Gal-GalNAc disaccharide, further modified by two N-acetylneuraminic acids.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • CC-1 antibody
      • CC-3 antibody
      • CCL14 antibody
      • CCL14_HUMAN antibody
      • chemokine (C-C motif) ligand 14 antibody
      • Chemokine CC-1/CC-3 antibody
      • chemokine CC1 antibody
      • chemokine CC3 antibody
      • chemokine HCC1 antibody
      • chemokine HCC3 antibody
      • CKb1 antibody
      • HCC-1(1-74) antibody
      • HCC-1(9-74) antibody
      • HCC-1/HCC-3 antibody
      • HCC-3 antibody
      • HCC1 antibody
      • HEMOFILTRATE CC CHEMOKINE 1 antibody
      • MCIF antibody
      • NCC-2 antibody
      • NCC2 antibody
      • new CC chemokine 2 antibody
      • SCYA14 antibody
      • SCYL2 antibody
      • small inducible cytokine subfamily A (Cys-Cys), member 14 antibody
      • Small-inducible cytokine A14 antibody
      • SY14 antibody
      see all

    Anti-CCL14 antibody images

    • Western blot against tagged recombinant protein immunogen using ab55752 CCL14 antibody at 1ug/ml. Predicted band size of immunogen is 36 kDa

    References for Anti-CCL14 antibody (ab55752)

    ab55752 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab55752.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"