• Product nameAnti-CCM2 antibody
    See all CCM2 primary antibodies
  • Description
    Mouse polyclonal to CCM2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length Human CCM2 protein (NP_113631.1).

  • Positive control
    • Human placenta tissue lysate. Cell lysate from transfected 293T cells.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 1 x PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products


Our Abpromise guarantee covers the use of ab88835 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 49 kDa.


  • FunctionMay function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock.
  • Involvement in diseaseDefects in CCM2 are the cause of cerebral cavernous malformations type 2 (CCM2) [MIM:603284]. Cerebral cavernous malformations (CCMs) are congenital vascular anomalies of the central nervous system that can result in hemorrhagic stroke, seizures, recurrent headaches, and focal neurologic deficits. CCMs have an incidence of 0.1%-0.5% in the general population and are usually present clinically during the 3rd to 5th decades of life. The lesions are characterized by grossly enlarged blood vessels consisting of a single layer of endothelium and without any intervening neural tissue, ranging in diameter from a few millimeters to several centimeters.
  • Sequence similaritiesContains 1 PID domain.
  • Cellular localizationCytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • C7orf22 antibody
    • Ccm2 antibody
    • CCM2 gene antibody
    • CCM2_HUMAN antibody
    • Cerebral cavernous malformation 2 antibody
    • Cerebral cavernous malformations 2 protein antibody
    • Chromosome 7 open reading frame 22 antibody
    • Malcavernin antibody
    • MGC4067 antibody
    • MGC4607 antibody
    • MGC74868 antibody
    • OSM antibody
    • Osmosensing scaffold for MEKK3 antibody
    • OTTHUMP00000159554 antibody
    • OTTHUMP00000214270 antibody
    • OTTHUMP00000214271 antibody
    • OTTHUMP00000214273 antibody
    • PP10187 antibody
    see all

Anti-CCM2 antibody images

  • Anti-CCM2 antibody (ab88835) at 1 µg/ml + Human placenta tissue lysate at 50 µg

    Predicted band size : 49 kDa
    Observed band size : 49 kDa
  • All lanes : Anti-CCM2 antibody (ab88835) at 1 µg/ml

    Lane 1 : cell lysate from CCM2 transfected 293T cell lysate
    Lane 2 : cell lysate from non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Predicted band size : 49 kDa
    Observed band size : ~60 kDa (why is the actual band size different from the predicted?)

References for Anti-CCM2 antibody (ab88835)

ab88835 has not yet been referenced specifically in any publications.

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