Overview

  • Product nameAnti-CCNDBP1 antibody
    See all CCNDBP1 primary antibodies
  • Description
    Goat polyclonal to CCNDBP1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Dog, Orangutan
  • Immunogen

    Synthetic peptide:

    C-NRIKELTQSELEL

    , corresponding to C terminal amino acids 348-360 of Human CCNDBP1.

  • Positive control
    • Human Brain cortex and Human prostate tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab110868 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionMay negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.
  • Tissue specificityUbiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.
  • Sequence similaritiesBelongs to the CCNDBP1 family.
  • Developmental stageExpression may increase during differentiation.
  • Post-translational
    modifications
    Phosphorylated.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • AU022347 antibody
    • CCDB1_HUMAN antibody
    • CCNDBP 1 antibody
    • Ccndbp1 antibody
    • Cyclin D type binding protein 1 antibody
    • Cyclin-D1-binding protein 1 antibody
    • D type cyclin interacting protein 1 antibody
    • DIP 1 antibody
    • DIP1 antibody
    • GCIP antibody
    • Grap 2 and cyclin D interacting protein antibody
    • Grap 2 cyclin D interacting protein GCIP antibody
    • Grap 2 cyclin interacting protein antibody
    • Grap2 and cyclin D interacting protein antibody
    • Grap2 and cyclin-D-interacting protein antibody
    • Grap2 cyclin D interacting protein GCIP antibody
    • Grap2 cyclin interacting protein antibody
    • HHM antibody
    • HHM protein antibody
    • Human homolog of Maid antibody
    • MAID antibody
    • MAID protein antibody
    • Maternal inhibition of differentiation antibody
    • MGC109078 antibody
    • OTTMUSP00000017037 antibody
    • RP23 263D22.2 antibody
    • SECC 8 antibody
    • SSEC 8 antibody
    • Stage specific embryonic cDNA 8 antibody
    see all

Anti-CCNDBP1 antibody images

  • ab110868 at 3.75 µg/ml staining CCNDBP1 in Formalin-fixed, Paraffin-embedded Human Brain cortex tissue by Immunohistochemistry.
  • ab110868 at 3.75 µg/ml staining CCNDBP1 in Formalin-fixed, Paraffin-embedded Human Prostate tissue by Immunohistochemistry.

References for Anti-CCNDBP1 antibody (ab110868)

ab110868 has not yet been referenced specifically in any publications.

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