Overview

  • Product nameAnti-CCNDBP1 antibody
    See all CCNDBP1 primary antibodies
  • Description
    Mouse monoclonal to CCNDBP1
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Orangutan
  • Immunogen

    Recombinant fragment: LVAENGKKDQ VAQMADIVDI SDEISPSVDD LALSIYPPMC HLTVRINSAK LVSVLKKALE ITKASHVTPQ PEDSWIPLLI NAIDHCMNRI KELTQSELEL , corresponding to amino acids 261-360 of human CCNDBP1 (NP_036274) with a 26 kDa tag

  • Positive control
    • CCNDBP1 transfected 293T cell lysate; recombinant tagged fragment of human CCNDBP1 (the immunogen).

Properties

Applications

Our Abpromise guarantee covers the use of ab77113 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 40 kDa.
ELISA Use at an assay dependent dilution.

Target

  • FunctionMay negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.
  • Tissue specificityUbiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.
  • Sequence similaritiesBelongs to the CCNDBP1 family.
  • Developmental stageExpression may increase during differentiation.
  • Post-translational
    modifications
    Phosphorylated.
  • Cellular localizationCytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • AU022347 antibody
    • CCDB1_HUMAN antibody
    • CCNDBP 1 antibody
    • Ccndbp1 antibody
    • Cyclin D type binding protein 1 antibody
    • Cyclin-D1-binding protein 1 antibody
    • D type cyclin interacting protein 1 antibody
    • DIP 1 antibody
    • DIP1 antibody
    • GCIP antibody
    • Grap 2 and cyclin D interacting protein antibody
    • Grap 2 cyclin D interacting protein GCIP antibody
    • Grap 2 cyclin interacting protein antibody
    • Grap2 and cyclin D interacting protein antibody
    • Grap2 and cyclin-D-interacting protein antibody
    • Grap2 cyclin D interacting protein GCIP antibody
    • Grap2 cyclin interacting protein antibody
    • HHM antibody
    • HHM protein antibody
    • Human homolog of Maid antibody
    • MAID antibody
    • MAID protein antibody
    • Maternal inhibition of differentiation antibody
    • MGC109078 antibody
    • OTTMUSP00000017037 antibody
    • RP23 263D22.2 antibody
    • SECC 8 antibody
    • SSEC 8 antibody
    • Stage specific embryonic cDNA 8 antibody
    see all

Anti-CCNDBP1 antibody images

  • Anti-CCNDBP1 antibody (ab77113) at 1/500 dilution + recombinant tagged fragment of human CCNDBP1 (the immunogen) at 0.2 µg

    Secondary
    Goat anti-Mouse IgG (H&L)-HRP at 1/5000 dilution

    Predicted band size : 40 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-CCNDBP1 antibody (ab77113) at 1/500 dilution

    Lane 1 : CCNDBP1 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 40 kDa
    Observed band size : 40 kDa

References for Anti-CCNDBP1 antibody (ab77113)

ab77113 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab77113.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"