Overview

  • Product nameAnti-CCR2 antibody [48607.121]
    See all CCR2 primary antibodies
  • Description
    Mouse monoclonal [48607.121] to CCR2
  • SpecificityMonoclonal Anti-Human CCR2 reacts with CCR2 transfected cells and not the parent cell line by flow cytometry. The antibody shows no cross-reactivity with CCR5 transfected cells.
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human CCR2 transfected NSO mouse myeloma cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab10396 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 5µg for 105 cells. ab170192-Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.

Target

  • FunctionReceptor for the MCP-1, MCP-3 and MCP-4 chemokines. Transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C C chemokine receptor type 2 antibody
    • C C CKR 2 antibody
    • C-C chemokine receptor type 2 antibody
    • C-C CKR-2 antibody
    • CC chemokine receptor type 2 antibody
    • CC CKR 2 antibody
    • CC-CKR-2 antibody
    • CCCKR2 antibody
    • CCR 2 antibody
    • CCR-2 antibody
    • CCR1L antibody
    • CCR2 antibody
    • CCR2_HUMAN antibody
    • CCR2A antibody
    • CCR2B antibody
    • CCR5L antibody
    • CD192 antibody
    • CD192 antigen antibody
    • Chemokine C C motif receptor 2 antibody
    • Chemokine CC Motif Receptor 2 antibody
    • CKR 2 antibody
    • CKR2 antibody
    • CKR2A antibody
    • CKR2B antibody
    • CMKBR2 antibody
    • MCP 1 R antibody
    • MCP-1-R antibody
    • MCP1 RECEPTOR antibody
    • MCP1R antibody
    • Monocyte chemoattractant protein 1 receptor antibody
    • Monocyte Chemotactic Protein 1 Receptor antibody
    • Monocyte Chemotactic Protein 1 Receptor antibody
    see all

References for Anti-CCR2 antibody [48607.121] (ab10396)

This product has been referenced in:
  • Brown CE  et al. Tumor-derived chemokine MCP-1/CCL2 is sufficient for mediating tumor tropism of adoptively transferred T cells. J Immunol 179:3332-41 (2007). Flow Cyt ; Human . Read more (PubMed: 17709550) »
  • Brown CE  et al. Tumor-derived chemokine MCP-1/CCL2 is sufficient for mediating tumor tropism of adoptively transferred T cells. J Immunol 179:3332-41 (2007). Flow Cyt ; Human . Read more (PubMed: 17709550) »

See all 2 Publications for this product

Product Wall

Application Blocking
Sample Human Cultured Cells (Human stromal cell (WPMY-1))
Specification Human stromal cell (WPMY-1)
Username

Miss. Junghyun Kim

Verified customer

Submitted Jun 02 2015

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"