Overview

  • Product name
    Anti-CCR2 antibody [7A7]
    See all CCR2 primary antibodies
  • Description
    Mouse monoclonal [7A7] to CCR2
  • Specificity
    The specificity of ab176390 was verified by flow cytometry with cells expressing the recombinant protein.
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Other Immunogen Type corresponding to Human CCR2. (DNA vaccine).
    Database link: P41597

  • Positive control
    • Human tonsil tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab176390 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.

Pretreatment with Proteinase K is required.

Target

  • Function
    Receptor for the MCP-1, MCP-3 and MCP-4 chemokines. Transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C C chemokine receptor type 2 antibody
    • C C CKR 2 antibody
    • C-C chemokine receptor type 2 antibody
    • C-C CKR-2 antibody
    • CC chemokine receptor type 2 antibody
    • CC CKR 2 antibody
    • CC-CKR-2 antibody
    • CCCKR2 antibody
    • CCR 2 antibody
    • CCR-2 antibody
    • CCR1L antibody
    • CCR2 antibody
    • CCR2_HUMAN antibody
    • CCR2A antibody
    • CCR2B antibody
    • CCR5L antibody
    • CD192 antibody
    • CD192 antigen antibody
    • Chemokine C C motif receptor 2 antibody
    • Chemokine CC Motif Receptor 2 antibody
    • CKR 2 antibody
    • CKR2 antibody
    • CKR2A antibody
    • CKR2B antibody
    • CMKBR2 antibody
    • MCP 1 R antibody
    • MCP-1-R antibody
    • MCP1 RECEPTOR antibody
    • MCP1R antibody
    • Monocyte chemoattractant protein 1 receptor antibody
    • Monocyte Chemotactic Protein 1 Receptor antibody
    • Monocyte Chemotactic Protein 1 Receptor antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human tonsil tissue labeling CCR2 with ab176390 at 1/50 dilution.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human tonsil tissue labeling CCR2 with ab176390 at 1/50 dilution.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human tonsil tissue labeling CCR2 with ab176390 at 1/50 dilution.

References

This product has been referenced in:
  • Guo X  et al. Hypoxia promotes glioma-associated macrophage infiltration via periostin and subsequent M2 polarization by upregulating TGF-beta and M-CSFR. Oncotarget 7:80521-80542 (2016). IHC, ICC/IF ; Human . Read more (PubMed: 27602954) »

See 1 Publication for this product

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There are currently no Customer reviews or Questions for ab176390.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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