• Product nameAnti-CCR6 antibody
    See all CCR6 primary antibodies
  • Description
    Rabbit polyclonal to CCR6
  • SpecificityNo cross reactivity with other proteins.
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human CCR6 aa 358-374 (C terminal). Different from the related rat and mouse sequences by two amino acids




Our Abpromise guarantee covers the use of ab78429 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.75 µg/ml. Predicted molecular weight: 42 kDa.
IHC-P Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.


  • FunctionReceptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level.
  • Tissue specificitySpleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells but not in natural killer cells, monocytes or granulocytes.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • BN 1 antibody
    • BN1 antibody
    • C C chemokine receptor type 6 antibody
    • C C CKR 6 antibody
    • C-C chemokine receptor type 6 antibody
    • C-C CKR-6 antibody
    • CC chemokine receptor type 6 antibody
    • CC CKR 6 antibody
    • CC R6 antibody
    • CC-CKR-6 antibody
    • CCCKR6 antibody
    • CCR 6 antibody
    • CCR-6 antibody
    • Ccr6 antibody
    • CCR6_HUMAN antibody
    • CD 196 antibody
    • CD196 antibody
    • CD196 antigen antibody
    • Chemokine (C C motif) receptor 6 antibody
    • Chemokine (C C) receptor 6 antibody
    • Chemokine (CC motif) receptor 6 antibody
    • Chemokine (CC) receptor 6 antibody
    • Chemokine receptor 6 antibody
    • Chemokine receptor like 3 antibody
    • Chemokine receptor-like 3 antibody
    • CKR 6 antibody
    • CKR L3 antibody
    • CKR-L3 antibody
    • CKR6 antibody
    • CKRL3 antibody
    • CMKBR 6 antibody
    • CMKBR6 antibody
    • DCR 2 antibody
    • DCR2 antibody
    • DRY 6 antibody
    • DRY6 antibody
    • G protein coupled receptor 29 antibody
    • G-protein coupled receptor 29 antibody
    • GPR 29 antibody
    • GPR CY4 antibody
    • GPR-CY4 antibody
    • GPR29 antibody
    • GPRCY 4 antibody
    • GPRCY4 antibody
    • LARC receptor antibody
    • Seven transmembrane receptor lymphocyte 22 antibody
    • STRL 22 antibody
    • STRL22 antibody
    see all

Anti-CCR6 antibody images

  • ab78429 at 0.5ug/ml staining CCR6 in human large intestine tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections). A Biotin-conjugated Goat anti-rabbit IgG was used as secondary at 1/200 dilution.

  • All lanes : Anti-CCR6 antibody (ab78429) at 0.75 µg/ml

    Lane 1 : Tissue lysate prepared from Rat Thymus
    Lane 2 : Whole cell lysate prepared from Human MCF7 cells
    Lane 3 : Whole cell lysate prepared from Hela cells
    Lane 4 : Cell lysate prepared from smmc cells

    Lysates/proteins at 50 µg per lane.

    HRP-conjugated Goat anti-rabbit IgG at 1/3000 dilution

    Predicted band size : 42 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)

References for Anti-CCR6 antibody (ab78429)

This product has been referenced in:
  • Chen H  et al. Serpin treatment suppresses inflammatory vascular lesions in temporal artery implants (TAI) from patients with giant cell arteritis. PLoS One 10:e0115482 (2015). Read more (PubMed: 25658487) »
  • Liu J  et al. CCR6 Is a Prognostic Marker for Overall Survival in Patients with Colorectal Cancer, and Its Overexpression Enhances Metastasis In Vivo. PLoS One 9:e101137 (2014). WB ; Mouse . Read more (PubMed: 24979261) »

See all 2 Publications for this product

Product Wall

Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Dog Tissue sections (Mammary gland tumor/inflamatory infiltrate)
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: Tris EDTA
Permeabilization No
Specification Mammary gland tumor/inflamatory infiltrate
Blocking step Sérum and milk (one hour for each one) as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 2% · Temperature: 27°C
Fixative Formaldehyde

Abcam user community

Verified customer

Submitted Sep 27 2016

Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Blocking step BSA as blocking agent for 5 minute(s) · Concentration: 1% · Temperature: 20°C
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: sodium citrate
Sample Human Tissue sections (tonsil)
Specification tonsil
Permeabilization No
Fixative Formaldehyde

Dr. R Berahovich

Verified customer

Submitted May 09 2014

I will be happy to send the ab1659 to you as a replacement for ab78429 however I did look at the LSBio antibody I think you are talking about, cat #LS-C83958 and they only predict that it will react with mouse tissue based on sequence homology. I have...

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I have looked over all the information that you sent and you have tried all the variations in protocol that I can think of to try and get ab78429 to work in IHC. I would be happy to send you a replacement antibody however I would just like to say that ...

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