The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use 0.5µg for 105-8 cells. It is recommended that the staining incubation time be increased to at least 45 minutes at 4°C for optimal staining. Staining the cell sample in a final volume of 100 µl is recommended.
ab18450-Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
FunctionReceptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
Tissue specificityExpressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Lymphocyte Specific G Protein Coupled Peptide Receptor antibody
MIP 3 beta receptor antibody
MIP-3 beta receptor antibody
MIP3 Beta Receptor antibody
References for Anti-CCR7 antibody [3D12] (ab95665)
This product has been referenced in:
Geginat J et al. Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines. Blood101:4260-6 (2003).
Read more (PubMed: 12576317) »
Sallusto F et al. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature401:708-12 (1999).
Read more (PubMed: 10537110) »