The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesFlow Cyt: Use 1µg for 106 cells.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionReceptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
Tissue specificityExpressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Staining of C57Bl/6 splenocytes with FITC anti-mouse CD4 (GK1.5) and either 0.5 µg of ab93518 (right) or 0.5 µg of APC Rat IgG2a Iso Control (left). Cells were stained at 37°C for 0.5 hours and Fc receptor binding was blocked by staining cells with 5 µg/million cells anti-mouse CD16/32. Cells in the lymphocyte gate were used for analysis.
References for Anti-CCR7 antibody [4B12] (Allophycocyanin) (ab93518)
has not yet been referenced specifically in any publications.
Publishing research using ab93518? Please let us know so that we can cite the reference in this datasheet.
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