Overview

  • Product name
    Anti-CCR9 antibody [E99]
    See all CCR9 primary antibodies
  • Description
    Rabbit monoclonal [E99] to CCR9
  • Specificity
    The antibody is specific to CCR9. It does not cross react with other G protein coupled receptor 1 family members.
  • Tested applications
    Suitable for: WB, ICC, Flow Cytmore details
    Unsuitable for: IHC or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human CCR9 (N terminal). The exact sequence is proprietary. A synthetic peptide corresponding to an extracellular domain of human CCR9.

  • Positive control
    • K562 and Daudi cell lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Alternative versions available:

    Anti-CCR9 antibody (HRP) [E99] (ab201829)

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • Concentration information loading...
  • Clonality
    Monoclonal
  • Clone number
    E99
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab32556 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 45 kDa (predicted molecular weight: 41 kDa).
ICC 1/250.
Flow Cyt 1/40.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

  • Application notes
    Is unsuitable for IHC or IP.
  • Target

    • Relevance
      The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. Two alternatively spliced transcript variants have been described.
    • Cellular localization
      Cell membrane; Multi-pass membrane protein.
    • Database links
    • Alternative names
      • C C chemokine receptor D6 antibody
      • C C chemokine receptor type 9 antibody
      • C C CKR 9 antibody
      • CC Chemokine receptor CCR10 antibody
      • CC CKR 9 antibody
      • CCBP2 antibody
      • CCCKR9 antibody
      • CCR 9 antibody
      • CCR9 antibody
      • CDw199 antibody
      • CDw199 antigen antibody
      • Chemokine (C C motif) receptor 9 antibody
      • Chemokine (C C motif) receptor 9, isoform CRA_a antibody
      • Chemokine (C-C motif) receptor 9 isoform A antibody
      • Chemokine (C-C motif) receptor 9 isoform B antibody
      • Chemokine C C motif receptor 9 antibody
      • Chemokine C C receptor 10 antibody
      • Chemokine CC Motif Receptor 9 antibody
      • Chemokine receptor CCR 9 antibody
      • Chemokine receptor CCR9 antibody
      • Chemokine-binding protein D6 antibody
      • Cmkbr10 antibody
      • CMKBR9 antibody
      • G protein coupled receptor 28 antibody
      • GPR 28 antibody
      • GPR 9 6 antibody
      • GPR28 antibody
      • GPR96 antibody
      • OTTHUMP00000164653 antibody
      • OTTHUMP00000164654 antibody
      see all

    Images

    References

    This product has been referenced in:
    • Chen X  et al. Retinoic acid facilitates inactivated transmissible gastroenteritis virus induction of CD8(+) T-cell migration to the porcine gut. Sci Rep 6:24152 (2016). Flow Cyt . Read more (PubMed: 27080036) »
    • Maeda S  et al. Molecular cloning and expression analysis of the canine chemokine receptor CCR9. Vet Immunol Immunopathol 145:534-9 (2012). WB . Read more (PubMed: 22209203) »

    See all 3 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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