Overview

  • Product nameAnti-CCRK antibody
    See all CCRK primary antibodies
  • Description
    Rabbit polyclonal to CCRK
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 159-208 (FGLARVFSPD GSRLYTHQVA TRSVGCIMGE LLNGSPLFPG KNDIEQLCYV) of Human CCRK (NP_848519).

  • Positive control
    • RPMI-8226 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab122996 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 39 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionRequired for high-level Shh responses in the developing neural tube. Together with BROMI, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.
  • Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
    Contains 1 protein kinase domain.
  • Cellular localizationNucleus. Cytoplasm. Cell projection > cilium.
  • Information by UniProt
  • Database links
  • Alternative names
    • CAK kinase p42 antibody
    • CAK-kinase p42 antibody
    • CCRK antibody
    • CDCH antibody
    • CDK activating kinase p42 antibody
    • CDK-activating kinase p42 antibody
    • cdk20 antibody
    • CDK20_HUMAN antibody
    • Cell cycle related kinase antibody
    • Cell cycle-related kinase antibody
    • Cell division protein kinase 20 antibody
    • Cyclin dependent protein kinase H antibody
    • Cyclin kinase activating kinase p42 antibody
    • Cyclin-dependent kinase 20 antibody
    • Cyclin-dependent protein kinase H antibody
    • Cyclin-kinase-activating kinase p42 antibody
    • p42 antibody
    • PNQALRE antibody
    see all

Anti-CCRK antibody images

  • Anti-CCRK antibody (ab122996) at 1 µg/ml + RPMI-8226 cell lysate at 10 µg

    Predicted band size : 39 kDa

References for Anti-CCRK antibody (ab122996)

ab122996 has not yet been referenced specifically in any publications.

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