Overview

  • Product nameAnti-CCRK antibody
    See all CCRK primary antibodies
  • Description
    Rabbit polyclonal to CCRK
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    A KLH conjugated synthetic peptide selected from the N-terminal region of human CCRK.

  • Positive control
    • Mouse kidney tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab71485 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa).
ELISA 1/1000.

Target

  • FunctionRequired for high-level Shh responses in the developing neural tube. Together with BROMI, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.
  • Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
    Contains 1 protein kinase domain.
  • Cellular localizationNucleus. Cytoplasm. Cell projection > cilium.
  • Information by UniProt
  • Database links
  • Alternative names
    • CAK kinase p42 antibody
    • CAK-kinase p42 antibody
    • CCRK antibody
    • CDCH antibody
    • CDK activating kinase p42 antibody
    • CDK-activating kinase p42 antibody
    • cdk20 antibody
    • CDK20_HUMAN antibody
    • Cell cycle related kinase antibody
    • Cell cycle-related kinase antibody
    • Cell division protein kinase 20 antibody
    • Cyclin dependent protein kinase H antibody
    • Cyclin kinase activating kinase p42 antibody
    • Cyclin-dependent kinase 20 antibody
    • Cyclin-dependent protein kinase H antibody
    • Cyclin-kinase-activating kinase p42 antibody
    • p42 antibody
    • PNQALRE antibody
    see all

Anti-CCRK antibody images

  • Anti-CCRK antibody (ab71485) at 1/60 dilution + mouse kidney tissue lysate at 35 µg

    Predicted band size : 39 kDa
    Observed band size : 38 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 36 kDa,70 kDa,75 kDa. We are unsure as to the identity of these extra bands.

References for Anti-CCRK antibody (ab71485)

ab71485 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your reply.I have processed your request to receive ab122996 as free of charge replacement for ab71485, which did not work for you as guaranteed. The antibody ab122996, is currently out of stock, but is due to come back into stock on Janu...

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Thank you for your reply.I am sorry that you are continuing to have problems with ab71485 in western blot. I would be happy to send you a replacement antibody. I would recommend trying a different CCRK antibody, since you are having issues with current...

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Thank you for contacting Abcam. Based on the information available on the public website, it does seem as though ab71485 recognizes multiple bands, please see the image in the link below: - http://www.abcam.com/CCRK-antibody-ab71485.html#ab71485.jpg I ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"