Overview

  • Product name
  • Description
    Goat polyclonal to CCT3
  • Specificity
    ab106932 is expected to recognize isoforms NP_005989.3 and NP_001008800.1.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat
    Predicted to work with: Cow, Dog, Human, Pig, Cynomolgus monkey
  • Immunogen

    Synthetic peptide:

    C-GHKKKGDDQSRQGG

    , corresponding to C terminal amino acids 525-538 of Human CCT3 (NP_005989.3) or amino acids 487-500 (NP_001008800.1).

  • Positive control
    • Mouse and Rat Testis lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106932 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.01 - 0.03 µg/ml. Predicted molecular weight: 61 kDa.

Target

  • Function
    Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.
  • Sequence similarities
    Belongs to the TCP-1 chaperonin family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • CCT 3 antibody
    • CCT gamma antibody
    • CCT-gamma antibody
    • CCT3 antibody
    • CCTG antibody
    • Chaperonin containing TCP1 subunit 3 (gamma) antibody
    • Chaperonin containing TCP1 subunit 3 antibody
    • hTRiC5 antibody
    • PIG48 antibody
    • T complex protein 1 gamma subunit antibody
    • T complex protein 1 subunit gamma antibody
    • T-complex protein 1 subunit gamma antibody
    • TCP 1 gamma antibody
    • TCP-1-gamma antibody
    • TCP1 (t complex 1) ring complex polypeptide 5 antibody
    • TCPG_HUMAN antibody
    • TRIC5 antibody
    see all

Images

References

This product has been referenced in:
  • Tracy CM  et al. Programmed cell death protein 5 interacts with the cytosolic chaperonin containing tailless complex polypeptide 1 (CCT) to regulate ß-tubulin folding. J Biol Chem 289:4490-502 (2014). WB ; Human . Read more (PubMed: 24375412) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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