Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence

    Associated products

    Specifications

    Our Abpromise guarantee covers the use of ab109275 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Blocking - Blocking peptide for Anti-CD10 antibody (ab73409)

    • Additional notes

      - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
      - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
      - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
      - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
      - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

      Information available upon request.

    General Info

    • Alternative names
      • Atriopeptidase
      • CALLA
      • CD10
      • CD10 antigen
      • Common acute lymphocytic leukemia antigen
      • DKFZp686O16152
      • EC 3.4.24.11
      • Enkephalinase
      • EPN
      • Membrane metallo endopeptidase
      • Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase)
      • Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10)
      • Membrane metallo endopeptidase variant 1
      • Membrane metallo endopeptidase variant 2
      • Membrane metalloendopeptidase
      • Membrane metalloendopeptidase neutral endopeptidase enkephalinase
      • Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10
      • Membrane metalloendopeptidase variant 1
      • Membrane metalloendopeptidase variant 2
      • MGC126681
      • MGC126707
      • MME
      • NEP
      • NEP_HUMAN
      • Neprilysin
      • neprilysin-390
      • neprilysin-411
      • Neutral endopeptidase
      • Neutral endopeptidase 24.11
      • Neutral endopeptidase, membrane-associated
      • SFE
      • Skin fibroblast elastase
      see all
    • Function
      Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
    • Sequence similarities
      Belongs to the peptidase M13 family.
    • Cellular localization
      Cell membrane.
    • Information by UniProt

    References

    ab109275 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab109275.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up