Anti-CD105 antibody [MEM-226], prediluted (Allophycocyanin) (ab60902)

Overview

  • Product nameAnti-CD105 antibody [MEM-226], prediluted (Allophycocyanin)
    See all CD105 primary antibodies
  • Description
    Mouse monoclonal [MEM-226] to CD105, prediluted (Allophycocyanin)
  • ConjugationAllophycocyanin. Ex: 645nm, Em: 660nm
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant Vaccinia virus containing the human CD105 cDNA.

Properties

Applications

Our Abpromise guarantee covers the use of ab60902 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notesFlow Cyt: Use 10µl reagent/ 100ul of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMajor glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.
    • Tissue specificityEndoglin is restricted to endothelial cells in all tissues except bone marrow.
    • Involvement in diseaseDefects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • AI528660 antibody
      • AI662476 antibody
      • CD 105 antibody
      • CD105 antibody
      • CD105 antigen antibody
      • EGLN_HUMAN antibody
      • END antibody
      • Endoglin antibody
      • Eng antibody
      • FLJ41744 antibody
      • HHT1 antibody
      • ORW antibody
      • ORW1 antibody
      • Osler Rendu Weber syndrome 1 antibody
      • RP11 228B15.2 antibody
      • S-endoglin antibody
      • SN6 antibody
      see all

    References for Anti-CD105 antibody [MEM-226], prediluted (Allophycocyanin) (ab60902)

    This product has been referenced in:
    • Kurian L  et al. Conversion of human fibroblasts to angioblast-like progenitor cells. Nat Methods 10:77-83 (2013). Read more (PubMed: 23202434) »
    • McLean K  et al. Human ovarian carcinoma–associated mesenchymal stem cells regulate cancer stem cells and tumorigenesis via altered BMP production. J Clin Invest 121:3206-19 (2011). Flow Cyt ; Human . Read more (PubMed: 21737876) »

    See all 2 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab60902.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"