Overview

  • Product nameAnti-CD105 antibody [MEM-229] (FITC)
    See all CD105 primary antibodies
  • Description
    Mouse monoclonal [MEM-229] to CD105 (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • Tested applicationsSuitable for: ICC, WB, IHC-Fr, Flow Cytmore details
  • Species reactivity
    Reacts with: Human, Pig
  • Immunogen

    Recombinant vaccinia virus containing human CD105 (L-isoform) cDNA

Properties

Applications

Our Abpromise guarantee covers the use of ab53318 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Use under non reducing condition. Predicted molecular weight: 71 kDa.
IHC-Fr 1/200. Fix with acetone.
Flow Cyt Use 20µl for 106 cells.

Or 100µl of whole blood.

ab91362 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

Target

  • FunctionMajor glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.
  • Tissue specificityEndoglin is restricted to endothelial cells in all tissues except bone marrow.
  • Involvement in diseaseDefects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • AI528660 antibody
    • AI662476 antibody
    • CD 105 antibody
    • CD105 antibody
    • CD105 antigen antibody
    • EGLN_HUMAN antibody
    • END antibody
    • Endoglin antibody
    • Eng antibody
    • FLJ41744 antibody
    • HHT1 antibody
    • ORW antibody
    • ORW1 antibody
    • Osler Rendu Weber syndrome 1 antibody
    • RP11 228B15.2 antibody
    • S-endoglin antibody
    • SN6 antibody
    see all

References for Anti-CD105 antibody [MEM-229] (FITC) (ab53318)

This product has been referenced in:
  • Muinos-López E  et al. Hypoxia and Reactive Oxygen Species Homeostasis in Mesenchymal Progenitor Cells Define a Molecular Mechanism for Fracture Nonunion. Stem Cells 34:2342-53 (2016). Read more (PubMed: 27250101) »
  • Lee AY  et al. Comparative studies on proliferation, molecular markers and differentiation potential of mesenchymal stem cells from various tissues (adipose, bone marrow, ear skin, abdominal skin, and lung) and maintenance of multipotency during serial passages in miniature pig. Res Vet Sci 100:115-24 (2015). Flow Cyt ; Pig . Read more (PubMed: 25823860) »

See all 9 Publications for this product

Product Wall

Thank you for contacting us. ab99597 is an allophycocyanin conjugated secondary antibody specific to primary Mouse IgM, it would therefore recognise ab27316 (a Mouse IgM). It would not recognise IgG. For more details about secondary antibodies pl...

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Thank you for your enquiry. Unfortunately, the exact concentration of adjusted (prediluted) conjugates which are sold per TEST, is proprietary information and can not be released. Please use the recommended dilution of 20ul for 10e6 cells or 100µl ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"