Anti-CD105 antibody [SN6] (FITC) (ab11415)

Overview

  • Product nameAnti-CD105 antibody [SN6] (FITC)
    See all CD105 primary antibodies
  • Description
    Mouse monoclonal [SN6] to CD105 (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • Specificityab11415 recognises the human CD105 cell surface antigen. CD105 is expressed by endothelial cells, activated monocytes and some leukaemia cells.
  • Tested applicationsSuitable for: Flow Cytmore details
    Unsuitable for: IHC-P
  • Species reactivity
    Reacts with: Horse, Human
  • Immunogen

    Partially purified cell membrane antigens from fresh leukaemia cells.

  • General notesThis product should be stored undiluted. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Properties

Applications

Our Abpromise guarantee covers the use of ab11415 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration. Use neat. Use 10ul of the suggested working dilution to label 10E6 cells in 100ul.



ab91356-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
  • Application notesIs unsuitable for IHC-P.
  • Target

    • FunctionMajor glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.
    • Tissue specificityEndoglin is restricted to endothelial cells in all tissues except bone marrow.
    • Involvement in diseaseDefects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • AI528660 antibody
      • AI662476 antibody
      • CD 105 antibody
      • CD105 antibody
      • CD105 antigen antibody
      • EGLN_HUMAN antibody
      • END antibody
      • Endoglin antibody
      • Eng antibody
      • FLJ41744 antibody
      • HHT1 antibody
      • ORW antibody
      • ORW1 antibody
      • Osler Rendu Weber syndrome 1 antibody
      • RP11 228B15.2 antibody
      • S-endoglin antibody
      • SN6 antibody
      see all

    Anti-CD105 antibody [SN6] (FITC) images

    • ab11415 staining CD105 in human KG1 cells by Flow Cytometry analysis.

    References for Anti-CD105 antibody [SN6] (FITC) (ab11415)

    ab11415 has not yet been referenced specifically in any publications.

    Product Wall

    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application Flow Cytometry
    Fixation Paraformaldehyde
    Sample Horse Cell (mesenchymal stem cells and blood)
    Specification mesenchymal stem cells and blood
    Gating Strategy white cells of blood and mesenchymal stem cells
    Permeabilization No
    Username

    DANIELLE BARBERINI

    Verified customer

    Submitted Jul 01 2013

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"