Overview

  • Product name
  • Description
    Rabbit polyclonal to CD11a
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 950 - 1050 of Human CD11a.

    (Peptide available as ab90246.)

  • Positive control
    • This antibody gave a positive signal in the following Human tissue lysates: Thymus; Spleen.

Properties

Applications

Our Abpromise guarantee covers the use of ab78058 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
WB
  • Application notes
    WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 161 kDa (predicted molecular weight: 129 kDa).
    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
    • Tissue specificity
      Leukocytes.
    • Sequence similarities
      Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
      Contains 1 VWFA domain.
    • Domain
      The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
    • Cellular localization
      Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Lymphocyte function associated antigen, type 1, alpha subunit antibody
      • Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide antibody
      • Antigen CD11A antibody
      • CD 11a antibody
      • CD11 antigen-like family member A antibody
      • CD11a antibody
      • CD11a antigen antibody
      • Integrin Alpha L antibody
      • Integrin alpha-L antibody
      • Integrin gene promoter antibody
      • Integrin, alpha L (antigen CD11A (p180), lymphocyte function associated antigen 1; alpha polypeptide) antibody
      • ITAL_HUMAN antibody
      • Itgal antibody
      • ITGAL protein antibody
      • Leukocyte adhesion glycoprotein LFA 1 alpha chain antibody
      • Leukocyte adhesion glycoprotein LFA-1 alpha chain antibody
      • Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain antibody
      • Leukocyte function associated molecule 1 alpha chain antibody
      • Leukocyte function-associated molecule 1 alpha chain antibody
      • LFA 1 alpha (LFA1A) antibody
      • LFA 1 alpha antibody
      • LFA 1 antibody
      • LFA 1A antibody
      • LFA-1A antibody
      • LFA1A antibody
      • Ly15 antibody
      • Ly21 antibody
      • Lymphocyte function associated antigen 1 antibody
      • Lymphocyte Function Associated Antigen Type 1 alpha antibody
      • lymphocyte function-associated antigen 1, alpha polypeptide antibody
      • p180 antibody
      see all

    Images

    • All lanes : Anti-CD11a antibody (ab78058) at 1 µg/ml

      Lane 1 : Human thymus tissue lysate - total protein (ab30146)
      Lane 2 : Human spleen tissue lysate - total protein (ab29699)

      Lysates/proteins at 10 µg per lane.

      Secondary
      Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
      Developed using the ECL technique

      Performed under reducing conditions.

      Predicted band size : 129 kDa
      Observed band size : 161 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 28 kDa,46 kDa. We are unsure as to the identity of these extra bands.

      Exposure time : 20 minutes

    References

    ab78058 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab78058.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up