Anti-CD11+CD18 antibody [24] (FITC) (ab187835)

Overview

  • Product name
    Anti-CD11+CD18 antibody [24] (FITC)
    See all CD11+CD18 primary antibodies
  • Description
    Mouse monoclonal [24] to CD11+CD18 (FITC)
  • Host species
    Mouse
  • Conjugation
    FITC. Ex: 493nm, Em: 528nm
  • Specificity
    ab187835 recognises integrin alpha L,M,X/Beta 2 (CD11/CD18).
  • Tested applications
    Suitable for: Flow Cyt, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Tissue, cells or virus corresponding to Human CD11+CD18. (Fibronectin-purified Human monocytes).

Properties

Applications

Our Abpromise guarantee covers the use of ab187835 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

ICC/IF Use at an assay dependent concentration.

Target

  • Function
    Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
  • Tissue specificity
    Leukocytes.
  • Sequence similarities
    Belongs to the integrin alpha chain family.
    Contains 7 FG-GAP repeats.
    Contains 1 VWFA domain.
  • Domain
    The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide antibody
    • CD11 antigen-like family member A antibody
    • CD11a antibody
    • CD18 antibody
    • CR3 antibody
    • Integrin alpha-L antibody
    • Integrin beta 2 antibody
    • Integrin gene promoter antibody
    • ITAL_HUMAN antibody
    • Itgal antibody
    • ITGAM antibody
    • ITGB2 antibody
    • LAD antibody
    • Leukocyte adhesion glycoprotein LFA-1 alpha chain antibody
    • Leukocyte function-associated molecule 1 alpha chain antibody
    • LFA 1 alpha antibody
    • LFA 1 antibody
    • LFA-1A antibody
    • LFA1 antibody
    • LFA1A antibody
    • Lymphocyte function associated antigen 1 antibody
    • MAC1 antibody
    • MFI7 antibody
    • MO1A antibody
    see all

References

ab187835 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab187835.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up