Overview

  • Product name
    Anti-CD11+CD18 antibody [CVS 9]
    See all CD11+CD18 primary antibodies
  • Description
    Mouse monoclonal [CVS 9] to CD11+CD18
  • Host species
    Mouse
  • Specificity
    This antibody recognises the equine CD11a/CD18 cell surface antigen, expressed by all equine leucocytes.
  • Tested applications
    Suitable for: IHC-Fr, Flow Cytmore details
  • Species reactivity
    Reacts with: Horse
  • Immunogen

    Tissue/ cell preparation. Leuocytes (Horse).

Properties

Applications

Our Abpromise guarantee covers the use of ab23917 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/1.
Flow Cyt Use at an assay dependent concentration.

ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Target

  • Function
    Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
  • Tissue specificity
    Leukocytes.
  • Sequence similarities
    Belongs to the integrin alpha chain family.
    Contains 7 FG-GAP repeats.
    Contains 1 VWFA domain.
  • Domain
    The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide antibody
    • CD11 antigen-like family member A antibody
    • CD11a antibody
    • CD18 antibody
    • CR3 antibody
    • Integrin alpha-L antibody
    • Integrin beta 2 antibody
    • Integrin gene promoter antibody
    • ITAL_HUMAN antibody
    • Itgal antibody
    • ITGAM antibody
    • ITGB2 antibody
    • LAD antibody
    • Leukocyte adhesion glycoprotein LFA-1 alpha chain antibody
    • Leukocyte function-associated molecule 1 alpha chain antibody
    • LFA 1 alpha antibody
    • LFA 1 antibody
    • LFA-1A antibody
    • LFA1 antibody
    • LFA1A antibody
    • Lymphocyte function associated antigen 1 antibody
    • MAC1 antibody
    • MFI7 antibody
    • MO1A antibody
    see all

References

ab23917 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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