Specificityab114069 labels the OX-40 antigen found on both mouse CD4 and CD8 single positive activated T cells. This is in contrast to rat OX-40 which is only found on CD4 positive T blasts (not CD8). ab114069 does not block binding of the OX-40L.
Tumor necrosis factor receptor superfamily member 4 antibody
Txgp 1l antibody
References for Anti-CD134 / OX40 antibody [OX-86] (Biotin) (ab114069)
This product has been referenced in:
Kjaergaard J et al. Augmentation versus inhibition: effects of conjunctional OX-40 receptor monoclonal antibody and IL-2 treatment on adoptive immunotherapy of advanced tumor. J Immunol167:6669-77 (2001).
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al-Shamkhani A et al. OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand. Eur J Immunol26:1695-9 (1996).
Read more (PubMed: 8765008) »