Overview

  • Product nameAnti-CD134 / OX40 antibody [OX-86] (Biotin)
    See all CD134 / OX40 primary antibodies
  • Description
    Rat monoclonal [OX-86] to CD134 / OX40 (Biotin)
  • ConjugationBiotin
  • Specificityab114069 labels the OX-40 antigen found on both mouse CD4 and CD8 single positive activated T cells. This is in contrast to rat OX-40 which is only found on CD4 positive T blasts (not CD8). ab114069 does not block binding of the OX-40L.
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Recombinant Mouse OX-40 antigen

  • Positive control
    • Balb/c splenic cells
  • General notesFor long term storage, aliquot and freeze unused portion at -20oC in volumes appropriate for single usage. Avoid freeze/thaw cycles.

Properties

Applications

Our Abpromise guarantee covers the use of ab114069 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 1µg for 106 cells. ab18403-Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Target

  • FunctionReceptor for TNFSF4/OX40L/GP34.
  • Sequence similaritiesContains 4 TNFR-Cys repeats.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ACT 35 antibody
    • ACT35 antibody
    • ACT35 antigen antibody
    • ATC35 antigen antibody
    • CD 134 antibody
    • CD134 antibody
    • CD134 antigen antibody
    • IMD16 antibody
    • Lymphoid activation antigene ACT35 antibody
    • OX 40 antibody
    • OX40 antibody
    • OX40 antigen antibody
    • OX40 cell surface antigen antibody
    • OX40 homologue antibody
    • OX40L receptor antibody
    • TAX transcriptionally activated glycoprotein 1 receptor antibody
    • TAX transcriptionally-activated glycoprotein 1 receptor antibody
    • TNF receptor superfamily member 4 antibody
    • TNFRSF 4 antibody
    • TNFRSF4 antibody
    • TNR4_HUMAN antibody
    • Tumor necrosis factor receptor superfamily member 4 antibody
    • Txgp 1l antibody
    • Txgp1 antibody
    • Txgp1l antibody
    see all

References for Anti-CD134 / OX40 antibody [OX-86] (Biotin) (ab114069)

This product has been referenced in:
  • Kjaergaard J  et al. Augmentation versus inhibition: effects of conjunctional OX-40 receptor monoclonal antibody and IL-2 treatment on adoptive immunotherapy of advanced tumor. J Immunol 167:6669-77 (2001). Read more (PubMed: 11714839) »
  • al-Shamkhani A  et al. OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand. Eur J Immunol 26:1695-9 (1996). Flow Cyt ; Mouse . Read more (PubMed: 8765008) »

See all 2 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab114069.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"